Products Topotecan is commercially available in capsule form and as a lyophilizate (Hycamtin, generic). It has been approved in many countries since 1996. Structure and properties Topotecan (C23H23N3O5, Mr = 421.4 g/mol) is present in the drug as topotecan hydrochloride. It is a semisynthetic derivative of camptothecin, a plant alkaloid derived from the tree. Effects … Topotecan
Products Irinotecansucrosofate was approved in many countries in 2017 as a concentrate for the preparation of an infusion solution (Onivyde). Structure and properties Irinotecansucrosofate is a nanoliposomal formulation of irinotecan. The drug is present enclosed in liposomes and therefore has a much longer half-life than irinotecan. The formulation may also contribute to lower toxicity and … Irinotecansucrosofate
Products Irinotecan is commercially available as an infusion concentrate (Campto, generic). It has been approved in many countries since 1998. In 2017, the nanoliposomal formulation irinotecan sucrosofate was released (Onivyde). Structure and properties Irinotecan (C33H38N4O6, Mr = 586.7 g/mol) is a semisynthetic derivative of camptothecin, a plant alkaloid derived from the tree. In the drug … Irinotecan
