Bromfenac

Products Bromfenac is commercially available in the form of eye drops (Yellox). It was approved in the United States in 2005 and in the EU in 2011. It was registered in many countries in 2013. Structure and properties Bromfenac (C15H12BrNO3, Mr = 334.2 g/mol) is a benzophenone derivative. It is present in solution in drugs … Bromfenac

Clonixin

Products No medicines containing clonixin are approved in many countries, but other NSAIDs are available that can be used as substitutes. Clonix 300 mg capsules are available in Portugal. Structure and properties Clonixin (C13H11ClN2O2, Mr = 262.7 g/mol) is a derivative of nicotinic acid and aniline. It is structurally related to other NSAIDs. Effects Clonixin … Clonixin

Calcium Carbase Salad

Products Calcium carbasalate (carbasalate calcium) is commercially available in the form of tablets and effervescent tablets (Alcacyl, Alca C with vitamin C). It has been approved in many countries since 1935. Note: Alcacyl powder contains lysine acetyl salicylate. Structure and properties Calcium carbasalate (C19H18CaN2O9, Mr = 458.4 g/mol) exists as a white crystalline powder that … Calcium Carbase Salad

Nepafenac

Products Nepafenac is commercially available as an eye drop suspension in two different concentrations (Nevanac). It has been approved in many countries since 2008. Structure and properties Nepafenac (C15H14N2O2, Mr = 254.3 g/mol) exists as a yellow powder. It is an amide analog and a prodrug of amfenac. It passes rapidly through the cornea and … Nepafenac

Diflunisal

Products Diflunisal is no longer available in pharmaceuticals in many countries. Unisal is out of commerce. Structure and properties Diflunisal (C13H8F2O3, Mr = 250.2 g/mol) is a derivative of salicylic acid. It exists as a white crystalline powder that is practically insoluble in water. Effects Diflunisal (ATC N02BA11) is analgesic, antipyretic, and anti-inflammatory. Indications Pain, … Diflunisal

Mefenamic Acid

Products Mefenamic acid is commercially available in the form of film-coated tablets, capsules, suppositories, and oral suspension. The drug has been approved in many countries since 1965. In addition to the original Ponstan, various generics are available. In many countries, the drug is known to both specialists and the general public and is frequently taken. … Mefenamic Acid

Tiaprofenic Acid

Products Tiaprofenic acid is commercially available in the form of tablets (Surgam). The drug is not registered in many countries. Structure and properties Tiaprofenic acid (C14H12O3S, Mr = 260.3 g/mol) is a thiophene derivative and belongs to the arylpropionic acid derivatives. Effects Tiaprofenic acid (ATC M01AE11) has analgesic, anti-inflammatory, and antipyretic properties. The effects are … Tiaprofenic Acid

Nimesulid

Products Nimesulide is commercially available as tablets and granules (Nisulide, Aulin). It has been approved in many countries since 1991. Nisulide gel is no longer available. Structure and properties Nimesulide (C13H12N2O5S, Mr = 308.3 g/mol) belongs to the sulfonanilide group. It exists as a yellowish crystalline powder that is practically insoluble in water. Effects Nimesulide … Nimesulid

Lornoxicam

Products Lornoxicam was commercially available in the form of film-coated tablets (Xefo). It had been approved in many countries since 1997. It was discontinued in 2020. Structure and properties Lornoxicam (C13H10ClN3O4S2, Mr = 371.82 g/mol) belongs to the oxicam group and is practically insoluble in water. Lornoxicam is a chlorinated derivative of tenoxicam (Tilcotil). Effects … Lornoxicam

Flurbiprofen

Products Flurbiprofen is commercially available as dragées (Froben) and as flurbiprofen lozenges and spray (Strepsils Dolo, generics). It has been approved in many countries since 1977. Structure and properties Flurbiprofen (C15H13FO2, Mr = 244.2 g/mol) is a racemate and exists as a white crystalline powder that is practically insoluble in water. Flurbiprofen, like the structurally … Flurbiprofen

Flurbiprofen Lozenges

Products Flurbiprofen lozenges have been approved in many countries since 2009 (Strepsils Dolo, formerly Strepsils). In other countries, the drug has been on the market for years. Generics were approved for the first time in 2016. Structure and properties Flurbiprofen (C15H13FO2, Mr = 244.2 g/mol) is a racemate and exists as a white crystalline powder … Flurbiprofen Lozenges

Etodolac

Products Etodolac is commercially available as film-coated tablets and sustained-release film-coated tablets (Lodine, Lodine retard). It has been approved in many countries since 1987. Structure and properties Etodolac (C17H21NO3, Mr = 287.4 g/mol) is a racemate. The -enantiomer is pharmacologically more active. Etodolac exists as a white crystalline powder that is practically insoluble in water. … Etodolac