Therapeutic target Establishment of a euthyroid metabolic state (= thyroid levels in the normal range). Therapy recommendations In hypothyroidism, a TSH level greater than 10 mU/l is considered an absolute indication for therapy. At the same time, free T3 and free T4 may be decreased. Pregnancy and childbearing as well as a goiter or a … Hypothyroidism (Underactive Thyroid): Drug Therapy
The diagnosis of hypothyroidism is made primarily by the clinical picture and laboratory examination. Optional medical device diagnostics-depending on the results of the history, physical examination, laboratory diagnostics, and obligatory medical device diagnostics-are used for differential diagnosis. Thyroid ultrasonography (ultrasonography of the thyroid gland) – to visualize the size of the thyroid gland and to … Hypothyroidism (Underactive Thyroid): Diagnostic Tests
A deficiency symptom may indicate that there is an insufficient supply of vital nutrients. The complaint hypothyroidism indicates a vital nutrient deficiency for: Iodine The above vital substance recommendations were created with the help of medical experts. All statements are supported by scientific studies with high levels of evidence. For a therapy recommendation, only clinical … Hypothyroidism (Underactive Thyroid): Micronutrient Therapy
To prevent hypothyroidism (underactive thyroid), attention must be paid to reducing individual risk factors. Behavioral risk factors Diet Iodine deficiency – see micronutrient therapy.
The following symptoms and complaints may indicate hypothyroidism (underactive thyroid): Leading symptoms Basal metabolic rate Drop in body temperature → feeling cold, hypersensitivity to cold. Decreased sweating (hypohidrosis). Doughy, cool-dry skin especially on the face and hands and feet. Lusterless shaggy hair Weight gain (with poor appetite). Cardial (cardiovascular) Normal to bradycardia (heartbeat too slow: … Hypothyroidism (Underactive Thyroid): Symptoms, Complaints, Signs
Endocrine, nutritional, and metabolic diseases (E00-E90). Autoimmune thyroiditis – autoimmune disease of the thyroid gland; initially with increased secretion of thyroid hormones, later with gradual transition to hypothyroidism (hypothyroidism). Secondary hypothyroidism due toanterior pituitary insufficiency (HVL insufficiency; hypopituitarism / hypofunction of the pituitary gland). Struma multinodosa – nodular change in thyroid tissue. Cardiovascular system (I00-I99) … Hypothyroidism (Underactive Thyroid): Or something else? Differential Diagnosis
The following are the major diseases or complications that may be contributed to by hypothyroidism (underactive thyroid): Respiratory system (J00-J99) Pulmonary edema – edema (accumulation of water) in the lungs. Certain conditions originating in the perinatal period (P00-P96). Neurologic damage in the fetus (unborn). Endocrine, nutritional, and metabolic diseases (E00-E90). Obesity (overweight) Fetal/neonatal goiter Hyperhomocysteinemia … Hypothyroidism (Underactive Thyroid): Complications
A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body temperature, body weight, body height; further: Inspection (viewing) of skin, mucous membranes, and sclerae (white part of eye) [pasty, cool-dry skin especially on face and hands and feet; lackluster shaggy hair; myxedema: Skin is … Hypothyroidism (Underactive Thyroid): Examination
1st-order laboratory parameters-obligatory laboratory tests. TSH (thyroid-stimulating hormone). FT3 (triiodothyronine) and fT4 (thyroxine) TRH-TSH test Primary hypothyroidism Secondary hypothyroidism* TSH ↑ ↓ /normal fT3, fT4 ↓ ↓ * Most common causes of sec. Hypothyroidism are tumors, trauma, and hemorrhage in the pituitary gland area. Latent hypothyroidism Manifest hypothyroidism TSH ↑ ↑ fT3, fT4 (still) within … Hypothyroidism (Underactive Thyroid): Test and Diagnosis
Medical history (history of illness) represents an important component in the diagnosis of hypothyroidism (underactive thyroid). Family history Is there a frequent history of thyroid disease in your family? Are there any hereditary diseases in your family? Social anamnesis Current medical history/systemic medical history (somatic and psychological complaints). What symptoms have you noticed? Weight gain … Hypothyroidism (Underactive Thyroid): Medical History
Pathogenesis (development of disease) Iodine deficiency is still the most common cause of hypothyroidism worldwide. In congenital (inherited) hypothyroidism, the defect is most often due to thyroid dysgenesis (thyroid malformation), and less commonly to a genetic defect in hormone synthesis. The pathogenesis of autoimmune hypothyroidism is based in part on genetic disorders as well as … Hypothyroidism (Underactive Thyroid): Causes
General measures Review of permanent medication due topossible effect on existing disease. Regular check-ups Regular medical checkups Nutritional medicine Nutritional counseling based on nutritional analysis Nutritional recommendations according to a mixed diet taking into account the disease at hand. This means, among other things: Daily total of 5 servings of fresh vegetables and fruits (≥ … Hypothyroidism (Underactive Thyroid): Therapy
