1st order In chronic iridocyclitis with seclusio pupillae (adhesions of the pupil), YAG laser iridotomy (incision into the iris of the eye without removal of iris parts) is performed. In this procedure, the iris is cut. In cataracta complicata (cataract) due to iridocyclitis, cataract extraction (lens removal) can be performed.
Prevention factors (protective factors) Statin therapy – on statin therapy, patients have a 48% reduced risk of developing uveitis. One possible explanation is various antiinflammatory (“directed against inflammation”) and immunomodulatory (“modifying the immune system“) mechanisms.
The following symptoms and complaints may indicate iridocyclitis: Leading symptoms Dull pain in the area of the eye/forehead. Deterioration of vision Epiphora (Greek for “trickling of tears”; this refers to the leakage of lacrimal fluid over the eyelid margins). Photophobia (photophobia; light pain).
Pathogenesis (development of disease) Iridocyclitis can occur in many different diseases. Often, there is an immunologic cause (allergic-hypergic reaction to bacterial toxins). Etiology (Causes) Biographic causes Genetic burden – clustered association with HLA-B27 (HLA-B27-associated iridocyclitis). Disease-related causes Eyes and eye appendages (H00-H59). Heterochromocyclitis – chronic inflammation of the ciliary body associated with different coloration of … Iridocyclitis: Causes
Medical history (history of illness) represents an important component in the diagnosis of iridocyclitis. Family history Social history Current anamnesis/systemic anamnesis (somatic and psychological complaints). What symptoms have you noticed in the eye? (Dull pain in the area of the eye/forehead). How long have these symptoms been present? Are both eyes affected or only one … Iridocyclitis: Medical History
Eyes and ocular appendages (H00-H59). Acute glaucoma attack (glaucoma). Heterochromocyclitis – chronic inflammation of the ciliary body associated with different coloration of the iris. Idiopathic (without apparent cause) iridocyclitis. Keratitis (inflammation of the cornea) Conjunctivitis (conjunctivitis) Sympathetic ophthalmia – inflammation of the middle eye skin that occurs after injury/surgery and is seen in the healthy … Iridocyclitis: Or something else? Differential Diagnosis
The following are the most important diseases or complications that may be contributed to by iridocyclitis: Eyes and ocular appendages (H00-H59). Cataracta complicata – form of cataract. Corneal band degeneration Macular edema – accumulation of water in the area of the center of the retina. Phthisis bulbi – shrinkage of the eyeball; leads to blindness. … Iridocyclitis: Complications
A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body weight, height; further: Inspection (viewing). Skin and mucous membranes Eyes [epiphora (Greek for “trickling of tears”; this refers to the leakage of lacrimal fluid over the edges of the eyelids)] Ophthalmic examination – slit … Iridocyclitis: Examination
1st order laboratory parameters – obligatory laboratory tests. Conjunctival swab – if infection is suspected. Blood cultures – in case of sepsis (blood poisoning).
Therapeutic target Improvement of symptomatology. Therapy recommendations Anti-infectives (local/local; antibiotics, antivirals). To prevent synechiae, mydriatics (pupil-dilating drugs; anticholinergics) and glucocorticoids Further notes In patients with noninfectious uveitis intermedia, uveitis posterior, and panuveitis who respond inadequately to glucocorticoid therapy, adalimumab (human monoclonal antibody to tumor necrosis factor-α; TNF blocker) can be used. Adalimumab has delayed disease … Iridocyclitis: Drug Therapy
Obligatory medical device diagnostics. Slit lamp examination (slit lamp microscope; viewing of the eyeball under appropriate illumination and high magnification).
