Bone Marrow Inflammation or Osteomyelitis

Bone Marrow Inflammation (Osteomyelitis): Surgical Therapy

The following curative (curative) measures may be necessary for osteomyelitis: Debridement surgery: resection of the fistula tracts, removal of all infected necrotic tissue and bone (sequestrectomy); drainage, open wound treatment if necessary. Radical resection (complete or partial removal of the tissue section by surgery) of the affected region up to amputation. Explantation (removal of an … Bone Marrow Inflammation (Osteomyelitis): Surgical Therapy

Bone Marrow Inflammation (Osteomyelitis): Prevention

To prevent osteomyelitis (bone marrow inflammation), attention must be paid to reducing individual risk factors. Systemic risk factors Old people Newborns Nutrition Malnutrion (malnutrition) Consumption of stimulants Tobacco (smoking) Malignant neoplasms, unspecified. Diabetes mellitus (diabetes) Immune disorders, unspecified Hepatic insufficiency (liver weakness) Renal insufficiency (kidney weakness) Respiratory insufficiency (“respiratory weakness”). Medications: Immunosuppression due to chemotherapy … Bone Marrow Inflammation (Osteomyelitis): Prevention

Bone Marrow Inflammation (Osteomyelitis): Symptoms, Complaints, Signs

The following symptoms and complaints may indicate osteomyelitis (bone marrow inflammation): Acute osteomyelitis Pain in the affected region Swelling in the affected region/strong sensitivity to pressure With joint involvement forced posture, painful functional lock; possibly also effusion; later usually also reddening of the skin and possibly increased venous drawing Fever Chronic osteomyelitis If necessary, insidious … Bone Marrow Inflammation (Osteomyelitis): Symptoms, Complaints, Signs

Bone Marrow Inflammation (Osteomyelitis): Causes

Pathogenesis (disease development) In circa 80% of cases, osteomyelitis occurs after trauma (injury)/fracture (bone fracture) or surgery (exogenous form). In circa 20%, it is the endogenous form of osteomyelitis, in which pathogen seeding from an existing focus of inflammation occurs (hematogenous form). In osteomyelitis, infection of the bone by bacteria occurs. These occupy regions of … Bone Marrow Inflammation (Osteomyelitis): Causes

Bone Marrow Inflammation (Osteomyelitis): Examination

A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body temperature, body weight, body height; furthermore: Inspection (viewing). Skin (normal: intact; abrasions/wounds, redness, hematomas (bruises), scars) and mucous membranes [redness of skin and increased venous markings]. Gait pattern (fluid, limping). Body or joint posture … Bone Marrow Inflammation (Osteomyelitis): Examination

Bone Marrow Inflammation (Osteomyelitis): Test and Diagnosis

Laboratory parameters of the 1st order – obligatory laboratory tests. Small blood count Inflammatory parameters – CRP (C-reactive protein). Biopsies/tissue samples (histology) – Histologic (fine tissue) examination of bone samples does not provide a definitive diagnosis of osteomyelitis, but it does provide information on possible differential diagnoses, such as malignancies (cancer) complicated by infection. Microbiology … Bone Marrow Inflammation (Osteomyelitis): Test and Diagnosis

Bone Marrow Inflammation (Osteomyelitis): Drug Therapy

Therapeutic targets Pain relief Elimination of pathogens Avoidance of complications Therapy recommendations Symptomatic therapy: analgesia (pain relief) according to WHO staging scheme: Non-opioid analgesic (paracetamol, first-line agent). Low-potency opioid analgesic (e.g., tramadol) + non-opioid analgesic. High-potency opioid analgesic (eg, morphine) + non-opioid analgesic. If necessary, anti-inflammatory drugs / drugs that inhibit inflammation (non-steroidal anti-inflammatory drugs, … Bone Marrow Inflammation (Osteomyelitis): Drug Therapy

Bone Marrow Inflammation (Osteomyelitis): Diagnostic Tests

Obligatory medical device diagnostics. Radiograph of the affected region, in two planes. Optional medical device diagnostics – depending on the results of the history, physical examination, laboratory diagnostics and obligatory medical device diagnostics – for differential diagnosis. Magnetic resonance imaging(MRI; computer-assisted cross-sectional imaging method (using magnetic fields, that is, without X-rays)) – for further diagnosis. … Bone Marrow Inflammation (Osteomyelitis): Diagnostic Tests

Bone Marrow Inflammation (Osteomyelitis): Medical History

Medical history (history of illness) is an important component in the diagnosis of osteomyelitis (bone marrow inflammation). Family history Are there any diseases in your family that are common? Social history What is your profession? Current medical history/systemic history (somatic and psychological complaints). Are you experiencing pain? If yes, when does the pain occur? Where … Bone Marrow Inflammation (Osteomyelitis): Medical History

Bone Marrow Inflammation (Osteomyelitis): Or something else? Differential Diagnosis

Infectious and parasitic diseases (A00-B99). Tuberculosis Endocrine, nutritional and metabolic diseases (E00-E90). Diabetic osteoarthropathy – bone/joint changes caused by diabetes mellitus (diabetes). Musculoskeletal system and connective tissue (M00-M99). Paget’s disease – disease of the skeletal system with bone remodeling. Neoplasms – tumor diseases (C00-D48). Benign and malignant (benign and malignant) tumors, unspecified. Ewing’s sarcoma (bone … Bone Marrow Inflammation (Osteomyelitis): Or something else? Differential Diagnosis

Bone Marrow Inflammation (Osteomyelitis): Complications

The following are the most important diseases or complications that may be contributed to by osteomyelitis (bone marrow inflammation): Infectious and parasitic diseases (A00-B99). Sepsis (blood poisoning) Musculoskeletal system and connective tissue (M00-M99). Frequent recurrence (recurrence) of osteomyelitis. Bone destruction (bone destruction). Pathological fracture (bone fracture) Subacute or chronic multifocal (“occurring in multiple locations of … Bone Marrow Inflammation (Osteomyelitis): Complications