In malignant fibrous histiocytoma (MFH), removal in healthy individuals with a safety margin is the goal.
The following form of surgical therapy is performed:
- Wide resection – method of choice for malignant bone tumors.
- Procedure: wide and radical resection (surgical removal) of the tumor with a safety margin.
- After tumor removal, osteosynthesis (insertion of a spongiosaplasty) or reconstruction of the resulting bone defect is performed, e.g., in the form of a tumor endoprosthesis, a bone graft, or muscle, nerve, and vascular replacement plastics. For children, growing endoprostheses (joint replacement) are suitable.
- Through the use of mega endoprostheses amputations of the affected limb are now rarely necessary (“Ultima ratio” (last resort)).
Malignant fibrous histiocytoma shows finger-shaped outgrowths into the surrounding tissue, which explains both the high recurrence rate (recurrence of the disease) and the metastasis (formation of daughter tumors) observed. Therefore, surgical therapy should be performed with a safety distance of 2-3 cm into healthy tissue.
