The United Kingdom Expert Group on Vitamins and Minerals (EVM) last evaluated vitamins and minerals for safety in 2003 and set a so-called Safe Upper Level (SUL) or Guidance Level for each micronutrient, provided sufficient data were available. This SUL or Guidance Level reflects the safe maximum amount of a micronutrient that will not cause any side effects when taken daily from all sources for a lifetime.
| The maximum safe daily intake for pantothenic acid is 200 mg. The maximum safe daily intake for pantothenic acid is 33 times the EU recommended daily intake (Nutrient Reference Value, NRV). |
This value applies to adult men and women. Due to lack of studies, it does not apply to pregnant women and nursing mothers.
There are no reports of adverse effects from excessive intake of pantothenic acid from food or supplements.
In one study, no side effects occurred even after amounts of 2 g (2,000 mg) of pantothenic acid per day, taken over several weeks. This amount, at which no adverse effects were observed, is over 300 times greater than the NRV and 10 times greater than the maximum safe daily intake.
Adverse effects of excessive pantothenic acid intake were observed only above amounts of 10-20 g in the form of occasional diarrhea (diarrhea) and water retention (water retention).
