Laboratory parameters of the 1st order – obligatory laboratory tests.
- Small blood count
- Fasting glucose (fasting blood glucose)
- Blood gas analysis (ABG)
- If necessary, incl. determination of the carboxyhemoglobin (CO hemoglobin, CO-Hb) or methemoglobin (MetHb) value – if carbon monoxide poisoning (CO poisoning) is suspected.
- Liver parameters – alanine aminotransferase (ALT, GPT), aspartate aminotransferase (AST, GOT), glutamate dehydrogenase (GLDH) and gamma-glutamyl transferase (gamma-GT, GGT), alkaline phosphatase, bilirubin.
- Renal parameters – urea, creatinine, cystatin C or creatinine clearance, if necessary.
- Coagulation parameters – PTT, Quick
- Muscle parameters – creatinine kinase (CK), myoglobin.
- Urine drug screening (amphetamine, methamphetamine, barbiturates, benzodiazepines, cannabis (tetrahydrocannabinol), ecstasy (methylenedioxymethylamphetamine), cocaine, methadone, morphine, phencyclidine and TCA).
- Ethanol level
- Drug level
- Examination of toxic residues, food residues, etc.
- Toxicological testing (blood, urine, vomit, evidence, respiratory gas, gastric lavage fluid, hair, fingernails and toenails).
- MicroRNA-122 (miR-122), high mobility group box-1 (HMGB1), keratin-18 (K18) – predictors of paracetamol-associated liver injury (hepatotoxicity) [if positive → acetylcysteine (ACC) by i.v. infusion).
- Pregnancy test (quantitative HCG).
Urine and blood/serum samples should be collected as soon as possible and forwarded for laboratory diagnosis!
