Products The first agent in the GLP-1 receptor agonist group to be approved was exenatide (Byetta) in the United States in 2005 and in many countries and the EU in 2006. In the meantime, several other drugs have been registered (see below). These drugs are also known as incretin mimetics. They are commercially available as … GLP-1 Receptor Agonists
Products Lymecycline is commercially available in the form of capsules (Tetralysal). It was approved in many countries in 2005. Structure and properties Lymecycline (C29H38N4O10, Mr = 602.6 g/mol) is a water-soluble prodrug of the antibiotic tetracycline with the amino acid lysine. Lymecycline is better absorbed than tetracycline. Effects Lymecycline (ATC J01AA04) has bacteriostatic properties against … Lymecycline
Products Exenatide is commercially available as an injectable (Byetta, Bydureon). It was approved in the United States in 2005 as the first agent in the GLP-1 receptor agonist group (Byetta). In many countries, the drug was registered a year later. The long-acting Bydureon Pen was approved in many countries in 2012, with additional approval as … Exenatide
Pharmacodynamics and pharmacokinetics. When we take a tablet, we are usually interested in its immediate effects. The drug is supposed to relieve a headache or reduce symptoms of a cold. At the same time, we may think about the possible side effects it may trigger. The desired and undesired effects that a drug exerts on … ADME
Products Ezetimibe is commercially available in tablet form, as a monopreparation (Ezetrol, generic), and as a fixed combination with simvastatin (Inegy, generic) and with atorvastatin (Atozet). Also released is a combination with rosuvastatin. Ezetimibe was approved in many countries and in the United States in 2002. Generic and auto-generics entered the market in November 2017. … Ezetimibe
Definition and mechanisms A pharmacokinetic booster is an agent that improves the pharmacokinetic properties of another agent. It is a desirable drug interaction It can exert its effects at different levels (ADME): Absorption (uptake into the body). Distribution (distribution) Metabolism and first-pass metabolism (metabolization). Elimination (excretion) Pharmacokinetic enhancers can increase absorption, increase distribution to an … Pharmacokinetic Booster
Products Antacids are commercially available in the form of lozenges, chewable tablets, as a powder, and as a gel (suspension) for oral use, among others. Well-known brands in many countries include Rennie, Alucol, and Riopan. The first medicines were developed as early as the 19th century. Structure and properties The drugs contain active ingredients that … Antacids to Neutralise Stomach Acid
Products Green coffee is commercially available in many countries in the form of capsules, powder and toffees from various suppliers, among others. Ingredients Green coffee is made from raw and unroasted coffee beans. The powder or extracts are used. The effects are primarily attributed to the high content of chlorogenic acids. According to some sources, … Green Coffee
Products Multivitamin preparations are commercially available in the form of tablets, effervescent tablets, chewable tablets and juice, among others. Among the best-known brands in many countries are, for example, Burgerstein CELA, Centrum and Supradyn. Some products are approved as medicines and others as dietary supplements. Supradyn (Bayer) was originally manufactured by Roche and has been … Multivitamin Supplements
Products Hydrous alumina is commercially available in combination with magnesium hydroxide as a suspension and in the form of chewable tablets (Alucol). It has been approved in many countries since 1957. Structure and properties Alumina (Al2O3, Mr = 102.0 g/mol) is the oxide of aluminum. Hydrous alumina, as defined by the pharmacopoeia, contains 47 to … Alumina
Products Iron is available in the form of tablets, capsules, chewable tablets, drops, as a syrup, direct granules and as a solution for injection, among others (selection). These are approved drugs and dietary supplements. It is also combined with folic acid, with vitamin C and with other vitamins and minerals fix. Some dosage forms are … Iron
Products In many countries, injection solutions containing ferric carboxymaltose (Ferinject, 2007), ferrous sucrose (Venofer, 1949), ferumoxytol (Rienso, 2012), and ferric derisomaltose (ferric isomaltoside, Monofer, 2019) are commercially available. In other countries, other products with different compositions are available, for example, ferrous sodium gluconate. Iron dextrans are rarely used anymore because of the risk for severe … Iron Infusions
