Iron Maltol

Products Ferric maltol is commercially available in the form of hard capsules (Feraccru, some countries: Accrufer). It was approved in the EU in 2016 and in many countries in 2017. Structure and properties Ferric maltol contains ferric ions in a complex with three molecules of maltol (ferric trimaltol). Due to the complexation, iron is better … Iron Maltol

Litramine

Products Litramine is commercially available in the form of tablets (Fatcontrol Biomed). Litramine is not approved as a drug, but as a medical device. Structure and properties Litramine is a fiber complex of soluble and non-soluble fibers extracted from the leaves of the prickly pear cactus. Effects The insoluble Litramine fibers bind lipids from food … Litramine

Whey Protein

Products Whey protein is available in retail and specialty stores from various suppliers as powder without flavor or with different flavors. The German term is actually whey protein or whey protein. However, the English term has prevailed and is more common. Structure and properties “Whey protein” is the protein contained in whey. Whey is produced … Whey Protein

Liraglutide

Products Liraglutide was approved in many countries in 2009 as a solution for injection in a prefilled pen (Victoza). In 2014, a fixed-dose combination with insulin degludec was released (Xultophy); see IDegLira. In 2016, Saxenda was registered for the treatment of overweight and obesity. Its related successor, semaglutide, unlike liraglutide, only needs to be injected … Liraglutide

Vaginal Suppositories

Products Vaginal suppositories are commercially available as drugs and medical devices. Listed below are some active ingredients which are administered vaginally: Estrogens: estriol Progestins: progesterone Antifungals: Econazole, ciclopirox Antiparasitics: Metronidazole, Clindamycin Antiseptics: Povidone–iodine, formerly boric acid. Probiotics: Lactobacilli The egg-shaped vaginal suppositories are also called ovules (singular ovulum). Structure and properties Vaginal suppositories are dosage … Vaginal Suppositories

Valganciclovir

Products Valganciclovir is commercially available in the form of film-coated tablets (Valcyte). It has been approved in many countries since 2001. Generic versions were registered in 2014. Structure and properties Valganciclovir (C14H22N6O5, Mr = 354.4 g/mol) is an L-valine ester prodrug of ganciclovir and is present in the drug product as valganciclovir hydrochloride, a white … Valganciclovir

Prasugrel

Products Prasugrel is commercially available in the form of film-coated tablets (Efient). It was approved in many countries, in the EU and in the US in 2009. Generic versions were registered in 2019. Structure and properties Prasugrel (C20H20FNO3S, Mr = 373.4 g/mol) belongs to the group of thienopyridines and exists as a hydrochloride as a … Prasugrel

Alendronate

Products Alendronate is commercially available in the form of weekly tablets (Fosamax, generic). It is also combined fixed with vitamin D (cholecalciferol) (Fosavance, generic) and has been approved in many countries since 1996. Structure and properties Sodium alendronate (C4H12NNaO7P2 – 3H2O, Mr = 325.1 g/mol) exists as a white crystalline powder that is soluble in … Alendronate

Enalapril: Drug Effects, Side Effects, Dosage and Uses

Products Enalapril is commercially available in tablet form (Reniten, generics). It has been approved in many countries since 1984. The active ingredient is also combined fixed with hydrochlorothiazide. Structure and properties Enalapril (C20H28N2O5, 376.45 g/mol) is present in drugs as enalapril maleate, a white powder that is sparingly soluble in water. Enalapril is the prodrug … Enalapril: Drug Effects, Side Effects, Dosage and Uses

Emulsions

Products Many pharmaceuticals, cosmetics (personal care products), medical devices, and foods (e.g., milk, mayonnaise) are emulsions. Structure and properties Emulsions are liquid or semi-solid preparations for external or internal use. They are dispersed systems (dispersions) in which two or more liquid or semisolid phases are combined by emulsifiers, resulting in a mixture that is heterogeneous … Emulsions

Omeprazole: Drug Effects, Side Effects, Dosage and Uses

Products Omeprazole is commercially available in tablet, capsule, and injection/infusion forms and has been approved in many countries since 1988. In addition to the original Antramups, generics and the -enantiomer esomeprazole (Nexium) are also commercially available. At the end of March 2010, after pantoprazole, omeprazole was also approved for self-medication in many countries. In the … Omeprazole: Drug Effects, Side Effects, Dosage and Uses

First-Pass Metabolism

The effect of the first liver passage For a perorally administered pharmaceutical agent to exert its effects at the site of action, it usually must enter the systemic circulation. To do so, it must pass through the intestinal wall, the liver, and part of the circulatory system. Despite complete absorption in the intestine, the bioavailability … First-Pass Metabolism