Products Zofenopril was approved in many countries in 2000 (Zofenil, Zofenil plus + hydrochlorothiazide). The drugs went off the market on April 23, 2011. Structure and properties Zofenopril (C22H23NO4S2, Mr = 429.6 g/mol) Effects Zofenopril (ATC C09AA15) has antihypertensive properties and relieves cardiac stress. Indications Hypertension Acute myocardial infarction
Products Zinc pyrithione is commercially available as a shampoo (Squa-med). It has been approved as a drug in many countries since 1980. In addition, cosmetics and medical products containing the active ingredient are also available. Structure and properties Zinc pyrithione (C10H8N2O2S2Zn, Mr = 317.7 g/mol) is structurally related to dipyrithione. Effects Zinc pyrithione (ATC D11AC08) … Zinc Pyrithione
Products Zileuton is commercially available in the United States in tablet and powder form (Zyflo). It is not currently approved in many countries. Structure and properties Zileuton (C11H12N2O2S, Mr = 236.3 g/mol) is an almost odorless, white, crystalline powder that is practically insoluble in water. It exists as a racemate. Both enantiomers are pharmacologically active. … Zileuton
Products Medicines containing oxilofrine are not commercially available in many countries. In some countries, it has been marketed in the form of drops and dragées (Carnigen). Structure and properties Oxilofrin (C10H15NO2, Mr = 181.2 g/mol) is present in drugs as oxilofrine hydrochloride and is also known as methylsynephrine. It is structurally related to ephedrine and … Oxilofrin
Products Oxazepam is commercially available in tablet form (Seresta, Anxiolit). It has been approved in many countries since 1966. Structure and properties Oxazepam (C15H11ClN2O2, Mr = 286.7 g/mol) is a racemate. It exists as a white crystalline powder that is practically insoluble in water. Effects Oxazepam (ATC N05BA04) has antianxiety, sedative, sleep-inducing, anticonvulsant, and muscle … Oxazepam: Drug Effects, Side Effects, Dosage and Uses
Products Eribulin is commercially available as a solution for injection (Halaven). It was approved in many countries and in the EU in 2011. In the United States, it has been registered since 2010. Structure and properties Eribulin is present in drugs as eribulin mesilate (C40H59NO11 – CH4O3S, Mr = 826.0 g/mol), a white crystalline powder … Eribulin
Products Azacitidine is commercially available as a lyophilizate for the preparation of a suspension for injection (Vidaza, generic). It has been approved in many countries since 2006. Structure and properties Azacitidine (C8H12N4O5, Mr = 244.2 g/mol) is a derivative of the nucleoside cytidine found in nucleic acids. It belongs to the pyrimidine nucleoside analogues. Azacitidine … Azacitidine
Products Azilsartan has been approved in the United States and the EU in tablet form since 2011 (Edarbi). In many countries, it was registered in August 2012 as the 8th member of the sartan drug group. In 2014, a fixed combination with chlortalidone was approved (Edarbyclor). Structure Azilsartan (C25H20N4O5, Mr = 456.5 g/mol) is present … Azilsartan
Background The skin of jellyfish contains so-called cnidocytes, which are used against prey and enemies when they come into contact with the skin. When appropriately irritated, a cnidocyst is ejected at high speed like a kind of harpoon, injecting a venom deep into the victim’s skin. This venom causes mild to fatal toxic and allergic … Jellyfish Repellent
Products Quinagolide is commercially available in tablet form (Norprolac). It has been approved in many countries since 1994. Structure and properties Quinagolide (C20H33N3O3S, Mr = 395.56 g/mol) is a non-ergoline dopamine agonist with a similar structure to apomorphine. It is present in drugs as quinagolide hydrochloride. Effects Quinagolide (ATC G02CB04) has dopaminergic properties and inhibits … Quinagolide
Products Infliximab is commercially available as a powder for a concentrate for the preparation of an infusion solution (Remicade, biosimilars: Remsima, Inflectra). It has been approved in many countries since 1999. Biosimilars were released in 2015. Structure and properties Infliximab is a chimeric human murine IgG1κ monoclonal antibody with a molecular mass of 149.1 kDa … Infliximab: Drug Effects, Side Effects, Dosage and Uses
Products Abiraterone is commercially available in the form of film-coated tablets (Zytiga). It has been approved in many countries since 2011. Structure and properties Abiraterone acetate (C26H33NO2, Mr = 391.5 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a prodrug and is rapidly biotransformed in the body to … Abiraterone Acetate