Lactitol

Products Lacitol is commercially available as a powder in sachets and as a syrup (Importal). It has been approved in many countries since 1985. Structure and properties Lactitol is present in drugs as lactitol monohydrate (C12H24O11 – H2O, Mr = 362.3 g/mol). Lactitol monohydrate is a white crystalline powder that is very soluble in water. … Lactitol

CCR5 Antagonists

Effects CCR5 antagonists have antiviral against HIV. They are selective antagonists of the interaction between human CCR5 and HIV-1 gp120, preventing viral entry the cells. Indications For treatment of HIV infection as part of combination antiretroviral therapy. Active ingredients Maraviroc (Celsentri) Detailed information.

Ergot Alkaloids

Structure and properties Depending on the side chains, ergot alkaloids are classified into two different groups: Ergometrine-type ergot alkaloids (e.g., ergometrine, methylergometrine). Peptide-type ergot alkaloids (e.g., ergotamine, ergotoxine, bromocriptine). Effects Ergot alkaloids exhibit the following effects in varying degrees: Partial agonists at alpha-adrenoreceptors. Partial agonists at serotonin receptors Stimulation of dopamine receptors Contraction of vascular … Ergot Alkaloids

Ifosfamide

Products Ifosfamide is commercially available as a dry substance for intravenous infusion (Holoxan). It has been approved in many countries since 1979. Structure and properties Ifosfamide (C7H15Cl2N2O2P, Mr = 261.1 g/mol) is an oxazaphosphorine and nitrogen-lost derivative, and an analog of cyclophosphamide. Ifosfamide is a racemate and exists as a white, crystalline, hygroscopic powder that … Ifosfamide

Avanafil

Products Avanafil is commercially available in tablet form (Spedra, some countries: Stendra). It was approved in the US in April 2012, in the EU in 2013, and in many countries in 2016. Structure and properties Avanafil (C23H26ClN7O3, Mr = 483.95 g/mol) is a pyrimidine derivative. It exists as a white crystalline powder that is practically … Avanafil