Products VEGF inhibitors are commercially available as injectables from various suppliers. The first agent in this group to be approved was pegaptanib (Macugen) in 2004, which is now off the market in many countries. Structure and properties The currently available VEGF inhibitors are therapeutic proteins (biologics). They are antibodies, antibody fragments, and fusion proteins. They … VEGF Inhibitors
Definition and examples Me-too drugs are imitators of already approved and established drugs, which differ only slightly from their predecessors. Typical drug groups with many me-too drugs are the statins (e.g., pitavastatin), the ACE inhibitors (e.g., zofenopril), the sartans (e.g., azilsartan), and the SSRIs (e.g., vortioxetine). Me-too drugs are not generics, but active ingredients with … Me-Too Drugs
Summary The invention of magnetic resonance imaging (MRI for short) represents an enormous enrichment for medicine. Not only does it allow the millimeter-precise representation of the finest structures inside the body, but according to current knowledge it also has no harmful effect on the human organism. This can be explained by the fact that, in … What side effects can occur with an MRI?
Nausea In general, magnetic resonance imaging is a very gentle examination without side effects. Nevertheless, patients repeatedly describe complaints during the examination. The most common side effects include mild to moderate nausea. However, this is not due to the MRI itself, but rather to the administration of contrast medium, which is often necessary in order … Nausea | What side effects can occur with an MRI?
Definition and examples The duration of therapy or treatment defines the period of time during which a drug is administered preventively or therapeutically. The shortest duration of therapy occurs with a single dose. This involves a single administration of a drug without repetition. An example of this is the antifungal drug fluconazole for the treatment … Duration of Therapy
Products Ozenoxacin was approved in the United States in 2017 as a cream (Xepi). Structure and properties Ozenoxacin (C21H21N3O3, Mr = 363.4 g/mol) exists as a white to slightly yellow powder. Unlike most quinolones, it is not fluorinated. Ozenoxacin carries a pyridinyl group at position C-7. Effects Ozenoxacin has bactericidal properties and is effective against … Ozenoxacin
Duration of side effects In general, the side effects of antidepressants occur mainly at the beginning of a therapy. Instead, the desired antidepressive effect occurs with a delay of a few weeks, which increases the risk of premature discontinuation of therapy. However, it should be borne in mind that the side effects mostly diminish continuously … Duration of side effects | Side effects of antidepressants
Besides the desired mood-lifting effect, antidepressants naturally also have side effects. Interactions with other drugs must also be taken into account, as well as the presence of certain diseases, for example, which could be a contraindication. The type of side effect depends very much on the type of antidepressant. In the following some of these … Side effects of antidepressants
