Frostbite

Symptoms In localized frostbite, the skin becomes pale, cold, hard, and insensitive to touch and pain. Only when it warms and thaws does redness appear and severe, pulsating pain, burning, and tingling set in. In addition, edema and blisters may form and, in a severe course, tissue dies. Often affected are exposed parts of the … Frostbite

Dispensing Categories of Medicinal Products

Definition The dispensing of licensed medicines is strictly regulated by law in many countries. Drugs may be available by prescription (prescription-only), nonprescription, and over-the-counter. Typical dispensing points are pharmacies, drugstores and doctors’ offices, provided that self-dispensing is permitted by the canton. Category E drugs may also be sold in the retail trade, for example in … Dispensing Categories of Medicinal Products

Cortisone Tablets Effects and Side Effects

Products Cortisone tablets are medicinal products which are intended for ingestion and contain active substances from the group of glucocorticoids. The tablets, water-soluble tablets and sustained-release tablets are usually monopreparations, which are often divisible. Glucocorticoids were first used medicinally in the late 1940s. Structure and properties The glucocorticoids contained in the drugs are derived from … Cortisone Tablets Effects and Side Effects

Bite Wounds

Symptoms Bite wounds manifest as painful mechanical damage to the skin and underlying tissues, for example, tendons, muscles, and nerves. They often occur on the arms and hands and can be potentially dangerous and fatal. A major concern with a bite wound is the transmission of infectious diseases. Pathogens involved include , , , , … Bite Wounds

Retigabine (Ezogabine)

Products Retigabine was approved in many countries as film-coated tablets since 2011 (Trobalt). In the United States, it is referred to as ezogabine. It was discontinued in 2017. Structure Retigabine (C16H18FN3O2, Mr = 303.3 g/mol) is a carbamate that was developed starting from the analgesic flupirtine. The free primary amino group is -glucuronidated (see below). … Retigabine (Ezogabine)

Rheumatoid Arthritis Causes and Treatment

Symptoms Rheumatoid arthritis is a chronic, inflammatory and systemic joint disease. It manifests as pain, symmetrically tense, achy, warm, and swollen joints, swelling, and morning stiffness that lasts for more than an hour. Initially, the hands, wrists, and feet are most affected, but later numerous other joints are also affected. Over time, deformities and rheumatoid … Rheumatoid Arthritis Causes and Treatment

COVID-19

Symptoms Symptoms of Covid-19 include (selection): Fever Cough (irritating cough or with sputum) Respiratory disorders, shortness of breath, shortness of breath. Feeling sick, fatigue Cold symptoms: runny nose, stuffy nose, sore throat. Pain in the limbs, muscle and joint pain. Gastrointestinal complaints: Diarrhea, nausea, vomiting, abdominal pain. Nervous system: impairment of the sense of smell … COVID-19

Pethidine

Products Pethidine is commercially available as a solution for injection. It has been approved in many countries since 1947. The drug is subject to strict control as a narcotic and is available only by prescription. Structure and properties Pethidine (C15H21NO2, Mr = 247.3 g/mol) is a phenylpiperidine derivative. In pharmaceuticals, it is present as pethidine … Pethidine

Thiopental

Products Thiopental is commercially available as an injectable (generic). It has been approved in many countries since 1947. Structure and properties Thiopental (C11H18N2O2S, Mr = 242.3 g/mol) is present in the drug as thiopental sodium, a yellowish white, hygroscopic powder that is readily soluble in water. It is a lipophilic thiobarbiturate identical to pentobarbital except … Thiopental

Codeine: Drug Effects, Side Effects, Dosage and Uses

Products Codeine is available alone or in combination with other active ingredients in the form of tablets, effervescent tablets, capsules, dragées, syrups, drops, bronchial pastilles, and as suppositories. It is also combined fixedly with acetaminophen for the treatment of pain (see under codeine acetaminophen). Structure and properties Codeine (C18H21NO3, Mr = 299.36 g/mol) is -methylated … Codeine: Drug Effects, Side Effects, Dosage and Uses

Earache Causes and Treatment

Symptoms Pain in the ear (technical term: otalgia) can be unilateral or bilateral and persistent or intermittent. They vary in intensity and nature, can be extremely uncomfortable, and sometimes go away on their own. Ear pain is often accompanied by other symptoms, such as a discharge from the ear canal, difficulty hearing, a feeling of … Earache Causes and Treatment