Aliskiren

Products Aliskiren is commercially available in the form of film-coated tablets (Rasilez, Rasilez HCT + hydrochlorothiazide). It was approved in many countries, in the EU and in the United States in 2007 (Other brand name: Tekturna). Note: Other combination preparations, e.g., with amlodpine (Rasilamlo), are no longer available. Structure and properties Aliskiren (C30H53N3O6, Mr = … Aliskiren

Fosinopril

Products Fosinopril is commercially available in tablet form. It has been approved in many countries since 1991. The original fosinopril is no longer available. Only fixed combinations with hydrochlorothiazide are currently on the market (generics). Fosicomp is also off the market. Structure and properties Fosinopril (C30H46NO7P, Mr = 563.7 g/mol) is present in drugs as … Fosinopril

Renin-angiotensin-aldosterone System: Function, Role & Diseases

The renin-angiotensin-aldosterone system controls salt and water balance in the human body and also regulates blood pressure to a certain extent. Various organs, hormones, and enzymes are involved in this regulatory circuit. What is the renin-angiotensin-aldosterone system? The lungs, liver, and kidneys are involved in the regulatory circuit of the renin-angiotensin-aldosterone system. Water and salt … Renin-angiotensin-aldosterone System: Function, Role & Diseases

Imidapril

Products Imidapril is registered as a powder for oral solution (Prilium). It has been approved in many countries since 2004. Imidapril has also been used in humans, but no human medicines are currently registered in many countries (Tanatril). Structure and properties Imidapril (C20H27N3O6, Mr = 405.4 g/mol) is a prodrug and is biotransformed by ester … Imidapril

Angiotensin II: Effects, Uses & Risks

Drugs that rely on angiotensin II play a major role in increasing blood pressure and sodium concentration. They are commonly used drugs that are popular among patients suffering from low blood pressure due to their quite rare side effects. What is angiotensin II? Angiotensin, known since 1940, is responsible for regulating blood pressure and is … Angiotensin II: Effects, Uses & Risks