Strong-acting painkillers are grouped under the term opioids. They can lead to dependence if used in excess. What are opioids? Strong-acting painkillers are summarized under the term opioids. They can lead to dependence if used in excess. Opioids that are used as pain relievers are also called opioid analgesics. These agents exert a strong analgesic … Opioids: Effects, Uses & Risks
Phenothiazines are a subgroup of thiazines. They are used primarily as neuroleptics. What are phenothiazines? Phenothiazines are derivatives of phenothiazine that are of pharmacologic relevance. In medicine, they are used as neuroleptics. There they are also known as tricyclic neuroleptics. The history of phenothiazines can be traced back to the beginning of organic chemistry. In … Phenothiazines: Effects, Uses & Risks
Products Antiemetics are commercially available in the form of tablets, as melting tablets, as solutions (drops), and injectables, among others. They are also administered as suppositories because peroral administration is not possible. In many countries, the best-known antiemetics include domperidone (Motilium, generic) and meclozine, which, along with caffeine and pyridoxine, is contained in Itinerol B6. … Antiemetics: Drugs against Nausea or Vomiting
Products Granisetron is commercially available as film-coated tablets and as an infusion concentrate (Kytril, generic). It has been approved in many countries since 1991. A transdermal patch was approved in the EU in 2012 (Sancuso). Structure and properties Granisetron (C18H24N4O, Mr = 312.4 g/mol) is an indazole derivative. It is present in drugs as granisetron … Granisetron
Thiethylperazine is a medicinal agent that belongs to the phenothiazines. Thiethylperazine is an antiemetic, making it suitable for the drug treatment of vomiting, nausea, and dizzy spells. In addition, thiethylperazine is also used as an antipsychotic. Thiethylperazine has an antagonistic effect on the receptors of the neurological neurotransmitter dopamine. What is thiethylperazine? Synonymous names for … Thiethylperazine: Effects, Uses & Risks
Definition In an intravenous injection, a small volume of a drug is administered into a vein using a needle and syringe. The active ingredients disperse into the bloodstream and reach their site of action. For repeated administration, venous access is established with a peripheral venous catheter. Larger volumes can be infused during an intravenous infusion. … Intravenous Injection
Products Dolasetron (Anzemet) is no longer on the market in many countries. It had been approved since 1999. The solution for injection was withdrawn in 2011 because of possible adverse effects (prolongation of the QT interval, cardiac arrhythmias), and later the tablets also went off the market. Structure and properties Dolasetron (C19H20N2O3, Mr = 324.4 … Dolasetron
Symptoms Complaints include nausea and/or vomiting, which in a minority occur only in the morning, and in the majority also during the day. Because of throat irritation, additional throat clearing and coughing are often observed and, in a severe course, tightening of the rib muscles. Course For most pregnant women, normal, self-limiting symptoms with no … Pregnancy Vomiting
Products Aprepitant is commercially available in the form of capsules (Emend). It has been approved in many countries since 2003. Structure and properties Aprepitant (C23H21F7N4O3, Mr = 534.4 g/mol) is a morpholine and triazol-3-one derivative. It exists as a white crystalline powder that is practically insoluble in water. For intravenous use, the more water-soluble prodrug … Aprepitant
Symptoms Typical symptoms of gastroenteritis include: Watery diarrhea Nausea, vomiting Abdominal pain Lack of appetite Weakness, lack of strength, feeling sick Mild fever may occur As a complication, dangerous dehydration may occur. At risk are especially infants, young children, the elderly and people with immunosuppression. With noroviruses, the duration of illness is short, but it … Stomach Flu
Products Palonosetron is commercially available as a solution for injection and as soft capsules (Aloxi, generic). It has been approved in many countries since 2006. The capsules were registered in 2013. Also approved is a fixed combination of netupitant and palonosetron in capsule form; see netupitant palonosetron. Structure and properties Palonosetron (C19H24N2O, Mr = 296.4 … Palonosetron
Products Bendamustine is commercially available as a lyophilizate for the preparation of an infusion solution (ribomustine). It actually has good oral bioavailability when taken fasting, but is only administered parenterally. Generic drugs are registered. Bendamustine was developed in 1963 by Ozegowski et al. in Jena in what was then East Germany and was marketed only … Bendamustine
