Products Medicines containing zipeprol are no longer on the market in many countries. Mirsol is no longer available. Zipeprol is classified as a narcotic. Structure and properties Zipeprol (C23H32N2O3, Mr = 384.5 g/mol) is a disubstituted piperazine derivative with a non-opioid structure. Effects Zipeprol (ATC R05DB15) has antitussive properties. In addition, anticholinergic, antihistamine, local anesthetic, … Zipeprol
Products Mallow is available as an open product in pharmacies and drugstores and is commercially available as a tea from various suppliers. Mallow is an ingredient in breast tea (Species pectorales). Mallow extract is on the market as a liquid and ointment (Malvedrin) and is included in cosmetics such as shampoos and shower gels. Stem … Mallow: Medicinal Uses
Products Erdostein is commercially available in the form of capsules (Mucofor). It was developed at Edmond Pharma in Milan, Italy, and has been approved in many countries since 1994. Structure and properties Erdostein (C8H11NO4S2, Mr = 249.3 g/mol) is a prodrug. The effects are mediated by the free sulfhydryl groups (-SH) of the metabolites. The … Erdostein
Products Dihydrocodeine is commercially available as sustained-release tablets, drops, and syrup (Codicontin, Paracodin, Escotussin, Macatussin Syrup). It has been approved in many countries since 1957. Structure and properties Dihydrocodeine (C18H23NO3, Mr = 301.4 g/mol) is a hydrogenated derivative of codeine. It is present in drugs as dihydrocodeine thiocyanate, dihydrocodeine hydrochloride, or dihydrocodeine tartrate. Dihydrocodeine tartrate … Dihydrocodeine
Products Kratom is not currently approved as a drug or medical device in many countries. From our point of view, kratom should be classified as a narcotic from a purely technical point of view. However, according to information from Swissmedic, it is not legally a narcotic (as of 1/2015). In 2017, however, the ingredients mitragynine … Kratom
Products Benproperine is commercially available in the form of tablets (Tussafug). The drug is not registered in many countries. Structure and properties Benproperine (C21H27NO, Mr = 309.4 g/mol) is a piperidine derivative. It is present in the drug as a racemate and benproperine phosphate. Effects Benproperine (ATC R05DB02) has antitussive properties. It is not opioid … Benproperine
Products Codeine is available alone or in combination with other active ingredients in the form of tablets, effervescent tablets, capsules, dragées, syrups, drops, bronchial pastilles, and as suppositories. It is also combined fixedly with acetaminophen for the treatment of pain (see under codeine acetaminophen). Structure and properties Codeine (C18H21NO3, Mr = 299.36 g/mol) is -methylated … Codeine: Drug Effects, Side Effects, Dosage and Uses
Products Ivy extracts are included in finished drug products and are available, for example, as syrups, drops, suppositories, and effervescent tablets. Dried ivy leaves are available in pharmacies and drugstores in open form. However, tea preparation is not very common. Stem plant Common ivy L. of the Aralia family is a perennial and evergreen root … Ivy
Products Butamirate is commercially available as a syrup, drops, and depot tablets (e.g., NeoCitran cough suppressant, formerly Sinecod). It has been approved in many countries since 1965. Structure and properties Butamirate (C18H29NO3, Mr = 307.4 g/mol) is present in drugs as butamirate dihydrogen citrate. It has structural similarities to the antitussive butetamate. Butamirate is not … Butamirate
Products Antitussives are commercially available in the form of tablets, capsules, as cough syrups, and drops, among others. Structure and properties Antitussives do not have a uniform chemical structure. However, many are derived from natural opium alkaloids (opioids). Effects Antitussives have cough-irritating (antitussive) properties. They reduce the frequency and intensity of coughing attacks. Their effects … Antitussives
CYP450 Cytochromes P450s are a family of enzymes that are of paramount importance in drug biotransformation. The most important isoenzymes for drug metabolism are: CYP1A1, CYP1A2 CYP2B6 CYP2C9, CYP2C19 CYP2D6 CYP2E1 CYP3A4, CYP3A5 and CYP3A7 The number after the abbreviation CYP stands for the family, the following letter for the subfamily and the last number … Cytochrome P450 (CYP)
Products Medicinal products containing preparations of opium, such as the opium tincture or an opium extract, are used less frequently. In contrast, the pure alkaloids such as morphine and codeine and related opioids are very commonly used medicinally, especially in pain management. Opium and the opioids are subject to narcotics laws. Stem plant The opium … Opium Poppy