Products Lokivetmab was approved in the EU in 2017 and in many countries in 2018 in the form of a solution for injection (Cytopoint, Zoetis Belgium SA). Lokivetmab was the first monoclonal antibody to be cleared for animals. In the United States, locivetmab was approved in 2015 (Canine Atopic Dermatitis Immunotherapeutic). Structure and properties Lokivetmab … Lokivetmab
Products In many countries, medical products containing Ectoin include the following: Triofan hay fever, nasal spray (2%) and eye drops (2%). Triofan Naturel, nasal spray (2%) Sanadermil EctoinAcute cream (7%, for dermatitis). Collypan Dry Eyes, eye drops (0.5% Ectoin, 0.2% sodium hyaluronate). Structure and properties Ectoine or 2-methyl-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid (C6H10N2O2, Mr = 142.2 g/mol) exists … Ectoin
Symptoms Inflammatory reactions in the diaper area: Reddened, wet, scaly erosions. Often shiny surface Vesicles and pustules Itching Painful open skin Diaper dermatitis with candida infection: Sharply demarcated, moist shiny skin redness in the folds of the buttocks and genital area. Scaly fringe at the transition zones to the healthy skin. Scattering of pinhead-sized nodules … Diaper Rash: Symptoms, Causes, Treatment
Stem plant Boraginaceae, borage. Medicinal drug Boraginis herba – borage herb Boraginis flos – borage flowers Boraginis semen – borage seeds Ingredients Boraginis seminis oleum – borage seed oil: γ-linolenic acid, linoleic acid. Herb, flowers: pyrrolizidine alkaloids. Indications The oil is used as a dietary supplement, for example, in atopic dermatitis and in dyslipidemia, use … Borage
Products Ketotifen is commercially available in tablet form and as eye drops (Zaditen, Zabak). It has been approved in many countries since 1977. See also under ketotifen eye drops. Structure and properties Ketotifen (C19H19NOS, Mr = 309.43 g/mol) is a tricyclic benzocycloheptathiophene derivative structurally related to pizotifen (Mosegor, out of commerce). It is present in … Ketotifen
Symptoms Nummular eczema (from Latin , coin) is an inflammatory skin disease that manifests itself in sharply defined, coin-shaped rashes that primarily affect the extensor sides of the legs, arms, and trunk. The areas are weeping, inflamed (reddened), and may become dry, crusted, and itchy. Unlike cutaneous fungus, the lesions are filled in and do … Nummular Eczema
Products Cortisone mixed ointments are not commercially available as finished drug products. They are prepared in pharmacies as extemporaneous preparations. Usually, a cream or ointment containing cortisone is diluted by mixing it with an ingredient-free base, such as Excipial or Antidry. The concentration of the glucocorticoid decreases in the process. However, the risk for adverse … Cortisone Mixed Ointments
Products Ciclosporin is commercially available as capsules, a drinkable solution, and an infusion concentrate (Sandimmune, Sandimmune Neoral, generics). It has been approved in many countries since 1995. Neoral is the microemulsion formulation that has more stable bioavailability than traditional Sandimmune. In 2016, ciclosporin eye drops were approved (see there). Structure and properties Ciclosporin (C62H111N11O12, Mr … Ciclosporin
Products Methylprednisolone aceponate has been approved in many countries since 1991 and is commercially available as cream, ointment, and fatty ointment (Advantan). Structure and properties Methylprednisolone aceponate (C27H36O7, Mr = 472.6 g/mol) is a lipophilic and nonhalogenated glucocorticoid that is hydrolyzed in the skin by esterases to the active metabolite 6α-methylprednisolone-17-propionate. Effects Methylprednisolone aceponate (ATC … Methylprednisolone Aceponate
Symptoms Cradle cap often occurs in infants during the first months of life. It manifests as a yellowish, encrusted, greasy and scaly scalp and may be accompanied by redness. The rash is not itchy and does not pose a medical problem for the child. Redness may also occur around the eyes, on the neck, and … Cradle Cap
Products Janus kinase inhibitors are commercially available in the form of tablets and capsules with different galenics. Structure and properties The structure of Janus kinase inhibitors is characterized by nitrogen heterocycles, which are often condensed. Effects The agents have selective immunosuppressive, anti-inflammatory, and antiproliferative properties. The effects are based on inhibition of Janus kinases (JAK). … Janus Kinase Inhibitors
Symptoms Dandruff is white or slightly gray in color. While dry dandruff tends to be small and small-shaped, greasy dandruff develops larger and also thicker scales due to the adhesive property of sebum. The most affected area is usually the crown of the head, while the nape of the neck usually has little or no … Dandruff
