Products Azilsartan has been approved in the United States and the EU in tablet form since 2011 (Edarbi). In many countries, it was registered in August 2012 as the 8th member of the sartan drug group. In 2014, a fixed combination with chlortalidone was approved (Edarbyclor). Structure Azilsartan (C25H20N4O5, Mr = 456.5 g/mol) is present … Azilsartan
Products Febantel is commercially available in combination tablet and suspension form as a veterinary drug. It has been approved in many countries since 1988. Structure and properties Febantel (C20H22N4O6S, Mr = 446.5 g/mol) is a sample zimidazole and a guanidine derivative. It exists as a colorless powder and is insoluble in water and alcohol due … Febantel
Products Emedastine is commercially available in the form of eye drops (Emadine). It has been approved in many countries since 1999. Structure and properties Emedastine (C17H26N4O, Mr = 302.41 g/mol) is a benzimidazole and a methyl diazepine derivative. It is present in drugs as emedastinidifumarate, a white powder that is soluble in water. Effects Emedastine … Emedastine
Products Astemizole was commercially available in tablet and suspension form (Hismanal). It has been withdrawn from the market in many countries because of potential adverse effects and is no longer available (see below). It may well be replaced by other, better-tolerated antihistamines, such as cetirizine, loratadine, and fexofenadine. Structure and properties Astemizole (C28H31FN4O, Mr = … Astemizole
Products Proton pump inhibitors (PPIs) are commercially available in many countries in the form of film-coated tablets, MUPS tablets, capsules, as granules for preparation of an oral suspension, and as injectable and infusion preparations. The first active ingredient from this group to be approved in many countries was omeprazole (Antra, Losec), developed by Astra in … Proton Pump Inhibitors
Products Rabeprazole is commercially available in the form of film-coated tablets (Pariet, generic). It has been approved in many countries since 1999. Generic versions have been available since 2012. Structure and properties Rabeprazole (C18H21N3O3S, Mr = 359.4 g/mol) is a benzimidazole and pyridine derivative and a racemate. It is present in drugs as rabeprazole sodium, … Rabeprazole
Products Mibefradil (Posicor tablets) was launched in many countries in 1996 and withdrawn from the market in 1998 because of potential interactions. It is no longer commercially available. Structure and properties Mibefradil (C29H38FN3O3, Mr = 495.6 g/mol) is a benzimidazole and a tetralol derivative. It is present in drugs as mibefradildihydrochloride. Effects Mibefradil (ATC C08CX01) … Mibefradil
Products Bilastin is commercially available in the form of tablets (Bilaxten). It was approved in many countries in 2011. In 2019, an oral solution and melting tablets for children were also registered. Structure and properties Bilastine (C28H37N3O3, Mr = 463.6 g/mol) is a benzimidazole and piperidine derivative. It was developed at FAES Farma in Spain. … Bilastin
Products Lansoprazole is commercially available in the form of capsules as meltable tablets (Agopton, generics). It has been approved in many countries since 1993. Structure and properties Lansoprazole (C16H14F3N3O2S, Mr = 369.4 g/mol) is a benzimidazole and pyridine derivative. It exists as a white to brownish-white, odorless, crystalline powder that is practically insoluble in water. … Lansoprazole
