Glaucoma: Causes and Treatment

Symptoms Glaucoma is a progressive eye disease that is initially asymptomatic. Patients have no symptoms until the optic nerve becomes increasingly damaged, which can lead to irreversible visual impairment with visual field loss and blindness. Glaucoma represents the most common cause of blindness. Causes The cause of the disease is usually an increase in intraocular … Glaucoma: Causes and Treatment

Travoprost

Products Travoprost is commercially available in the form of eye drops as a monopreparation (Travatan) and as a fixed combination with the beta-blocker timolol (Duotrav). It was approved in many countries in 2002. Generic versions were first released in 2016 and went on sale in 2017. Structure and properties Travoprost (C26H35F3O6, Mr = 500.55 g/mol) … Travoprost

Timolol

Products Timolol is commercially available in the form of eye drops and as an eye gel. In addition to the original Timoptic, generics and various fixed combinations with other antiglaucomatous agents are also commercially available (brinzolamide, brimonidine, dorzolamide, travoprost, latanoprost). Timolol has been approved in many countries since 1978. See also under timolol gel (hemangioma). … Timolol

Rosacea Causes and Treatment

Symptoms Rosacea is a chronic inflammatory skin disorder of the face that typically affects the cheeks, nose, chin, and central forehead symmetrically (Figure). The skin around the eyes is left out. It occurs more often in people with fair skin and in middle age, but it can occur in any skin type and at any … Rosacea Causes and Treatment

Brimonidine

Products Brimonidine is commercially available in the form of eye drops (Alphagan, generic). It is also available in combination with timolol (Combigan, generic) and has been approved in many countries since 1998. The active ingredient is also used for the external treatment of rosacea, see under the article Brimonidine gel. Finally, brimonidine is also combined … Brimonidine

Brimonidine Gel

Products Mirvaso brimonidine gel was approved in the EU in 2013 and in many countries in 2014. Structure and properties Brimonidine (C11H10BrN5, Mr = 292.1 g/mol) is present in the drug as brimonidine tartrate, a white to yellow powder that is soluble in water. It has a similar structure to clonidine and apraclonidine. Effects Brimonidine … Brimonidine Gel