Apraclonidine

Products Apraclonidine is commercially available in the form of eye drops (iopidine). It has been approved in many countries since 1995. Structure and properties Apraclonidine (C9H10Cl2N4, Mr = 245.1 g/mol) is an amino derivative of clonidine. It is present in the drug as apraclonidine hydrochloride, a white powder that is highly soluble in water. Effects … Apraclonidine

Dipivefrin

Products No medicines containing dipivefrin are registered in many countries. Eye drops are available in other countries. Structure and properties Dipivefrin (C19H29NO5, Mr = 351.4 g/mol) is an ester prodrug of epinephrine with two molecules of pivalic acid. It is present in the drug as dipivefrin hydrochloride. Effects Dipivefrin (ATC S01EA02) lowers intraocular pressure. Because … Dipivefrin

Brimonidine

Products Brimonidine is commercially available in the form of eye drops (Alphagan, generic). It is also available in combination with timolol (Combigan, generic) and has been approved in many countries since 1998. The active ingredient is also used for the external treatment of rosacea, see under the article Brimonidine gel. Finally, brimonidine is also combined … Brimonidine