Products Medicines containing zipeprol are no longer on the market in many countries. Mirsol is no longer available. Zipeprol is classified as a narcotic. Structure and properties Zipeprol (C23H32N2O3, Mr = 384.5 g/mol) is a disubstituted piperazine derivative with a non-opioid structure. Effects Zipeprol (ATC R05DB15) has antitussive properties. In addition, anticholinergic, antihistamine, local anesthetic, … Zipeprol
Products Butamirate is commercially available as a syrup, drops, and depot tablets (e.g., NeoCitran cough suppressant, formerly Sinecod). It has been approved in many countries since 1965. Structure and properties Butamirate (C18H29NO3, Mr = 307.4 g/mol) is present in drugs as butamirate dihydrogen citrate. It has structural similarities to the antitussive butetamate. Butamirate is not … Butamirate
Stem plant Droseraceae, round-leaved sundew. Medicinal drug Droserae herba – sundew herb. Preparations Droserae extractum ethanolicum liquidum Droserae extractum liquidum Droserae recentis herbae cum radice extractum ethanolicum liquidum Droserae tinctura Ingredients 1,4-Naphtoquinone derivatives, e.g., plumbagin. Effects Cough-irritant Bronchospasmolytic Indications for use Irritant cough Dosage As an infusion, mean daily dose 3 g. Adverse effects None … Sundew: Medicinal Uses, Effects, Indications
Products Methylephedrine is sold in many countries exclusively in the form of capsules in combination with other active ingredients (Tossamine plus). Structure and properties Methylephedrine (C11H17NO, Mr = 179.3 g/mol) Effects Methylephedrine has bronchospasmolytic properties. Indications Tossamine plus is approved for the treatment of cough not associated with excessive mucus production.
Composition (Pharmacopoeia) Marshmallow root (4000) 10 g Anise (crushed) 15 g Yellow cat’s paw flower (5600) 5 g Licorice root (4000) 10 g Mallow flowers 15 g Senega root (4000) 10 g Thyme 10 g Mullein flowers 15 g The herbal drugs are mixed. Preparations Specierum pectoralium extractum – extract from breast tea. Effects Expectorant … Breast Tea
Products Thyme is available in the form of tea bags and as an open product in pharmacies and drugstores. Numerous cold remedies contain preparations of thyme herb, for example, thyme ointments, tablets, bronchial pastilles, inhalations, cough syrups, baths, cold teas and drops. The essential oil is also on sale. Stem plant Both common thyme L. … Thyme
Products Ipratropium bromide is commercially available as an inhalation solution, metered-dose inhaler, and nasal spray (Atrovent, Rhinovent, generics). Combination preparations with beta2-sympathomimetics are also commercially available (Dospir, Berodual N, generics). Pharmacies also produce inhalation solutions with ipratropium bromide as extemporaneous preparations. The active ingredient has been approved in many countries since 1978. Structure and properties … Ipratropium Bromide
Products Vilanterol is commercially available as a fixed combination with fluticasone furoate in powder inhaler form (Relvar Ellipta / Breo Ellipta). It was approved in the US and EU in 2013 and in many countries in 2014. The fixed combination with umeclidinium bromide (Anoro Ellipta) was also registered in many countries in 2014. In 2017, … Vilanterol
Products Pirbuterol is available as a drug for inhalation in some countries (e.g., USA, Maxair). The drug is no longer approved in many countries. Structure and properties Pirbuterol (C12H20N2O3, Mr = 240.3 g/mol) is a pyridine derivative closely related structurally to salbutamol (Ventolin, generics), differing from it only in one nitrogen atom. It is present … Pirbuterol
Products Salmeterol is commercially available as metered-dose inhalers and discs (Serevent, Seretide + fluticasone). It has been approved in many countries since 1995. Structure and properties Salmeterol (C25H37NO4, Mr = 415.6) is present in the drugs as a racemate and as salmeterol xinafoate, a white powder that is sparingly soluble in water. It is structurally … Salmeterol
Products Indacaterol is commercially available as hard capsules with a powder for inhalation (Onbrez Breezhaler) and has been approved since 2010. It is also combined fixed with the LAMA glycopyrronium bromide (Ultibro Breezhaler, approved 2014). The fixed combination with mometasone furoate (Atectura Breezhaler) was registered for asthma therapy in 2020. Finally, a combination of indacaterol … Indacaterol
Products Morclofon is commercially available as a syrup (Nitux). It has been approved in many countries since 1979. Structure and properties Morclofon (C21H24ClNO5, Mr = 405.87 g/mol) is 4′-chloro-3,5-dimethoxy-4-(2-morpholinoethoxy)benzophenone. Effects Morclofon (ATC R05DB25) has central antitussive and bronchospasmolytic properties. It is an older drug. Modern registration studies are lacking. Indications For the treatment of irritable … Morclofon