Products Obeticholic acid is commercially available in the form of film-coated tablets (Ocaliva). It has been approved in the EU and US since 2016 and in many countries since 2018. Structure and properties Obeticholic acid (C26H44O4, Mr = 420.6 g/mol) exists as a white powder that is highly soluble in water at a high pH. … Obeticholic Acid
Products Calcifediol was approved in the United States in 2016 and in many countries in 2020 in extended-release capsule form (Rayaldee). Structure and properties Calcifediol (C27H44O2, Mr = 400.6 g/mol) is a hydroxylated derivative of vitamin D3 (cholecalciferol). It is 25-hydroxycholecalciferol or 25-hydroxyvitamin D3. Calcifediol is present in the drug as calcifediol monohydrate, a white … Calcifediol
Products Bezafibrate is commercially available in the form of sustained-release tablets (Cedur retard). It has been approved in many countries since 1979. Structure and properties Bezafibrate (C19H20ClNO4, Mr = 361.8 g/mol) lies as a white crystalline powder that is practically insoluble in water. Effects Bezafibrate (ATC C10AB02) primarily lowers elevated blood triglyceride levels. It has … Bezafibrate
Products Raloxifene is commercially available in the form of film-coated tablets (Evista). It has been approved in many countries since 2000. Structure and properties Raloxifene (C28H27NO4S, Mr = 473.6 g/mol) is present in the drug as raloxifene hydrochloride, a benzothiophene and white to yellowish powder that is sparingly soluble in water. Effects Raloxifene (ATC G03XC01) … Raloxifene
Products Doxycycline is commercially available in the form of tablets, capsules, and as a solution for injection (vibramycin, vibravenous, generic). It has been approved in many countries since 1972. Structure and properties Doxycycline (C22H24N2O8, Mr = 444.4 g/mol) is usually present in drugs as doxycycline hyclate. Some drugs also contain doxycycline monohydrate. These are yellow … Doxycycline: Drug Effects, Side Effects, Dosage and Uses
Products Naproxen has been approved in many countries since 1975 and is commercially available in the form of film-coated tablets (e.g., Apranax, Proxen, generics). Other dosage forms such as the suppositories and the juice are no longer available. Drugs with a deep dose have been available over the counter since 1999 (Aleve with 200 mg … Naproxen: Drug Effects, Side Effects, Dosage and Uses
