Products Minocycline is commercially available in the form of film-coated tablets (Minocin). It has been approved in many countries since 1984. Minac capsules are out of commerce. Topical medicines are additionally available in some countries. Structure and properties Minocylcine (C23H27N3O7, Mr = 457.5 g/mol) is present in drugs as minocycline hydrochloride, a yellow, crystalline, hygroscopic … Minocycline
Products Acarbose is commercially available in tablet form (Glucobay). It is usually combined with other agents such as metformin, insulin, or sulfonylureas to enhance the antidiabetic effect. Acarbose has been approved in many countries since 1986. Structure and properties Acarbose (C25H43NO18, Mr = 645.60 g/mol) is a pseudotetrasaccharide obtained from the bacterium by fermentation. It … Acarbose Effects and Side Effects
Definition Pharmaceutical agents are excreted primarily in the urine and, via the liver, in the bile in the stool. When excreted via the bile, they re-enter the small intestine, where they may be reabsorbed. They are transported back to the liver via the portal vein. This repetitive process is called the enterohepatic circulation. It prolongs … Enterohepatic Circulation
Products Ezetimibe is commercially available in tablet form, as a monopreparation (Ezetrol, generic), and as a fixed combination with simvastatin (Inegy, generic) and with atorvastatin (Atozet). Also released is a combination with rosuvastatin. Ezetimibe was approved in many countries and in the United States in 2002. Generic and auto-generics entered the market in November 2017. … Ezetimibe
Products Colestyramine is commercially available as a powder in sachets (Quantalan). It has been approved in many countries since 1990. Structure and properties Colestyramine is a strongly basic anion exchange resin in the chloride form, consisting of a styrene-divinylbenzene copolymer with quaternary ammonium groups. It exists as a white, fine, hygroscopic powder that is insoluble … Colestyramine: Drug Effects, Side Effects, Dosage and Uses
Products Lipid-lowering agents are mainly sold as tablets and capsules as monopreparations and combination preparations. Some other dosage forms exist, such as granules and injectables. Statins have established themselves as the most important group at present. Structure and properties The chemical structure of lipid-lowering agents is inconsistent. However, within the class, groups with comparable structures … Lipid-Lowering Agents
Cardiac glycosides are drugs that have a positive effect on the beating power of the heart while lowering the heart rate. They are used to treat heart disease. What are cardiac glycosides? Cardiac glycosides are often referred to as digitalis. This name is in reference to the foxglove (digitalis), which contains cardiac glycosides in fairly … Cardiac Glycosides: Effects, Uses & Risks
Products Methotrexate is commercially available as a solution for parenteral use and in tablet form. See also under methotrexate prefilled syringe (low-dose). Structure and properties Methotrexate (C20H22N8O5, Mr = 454.44 g/mol) is a dicarboxylic acid that exists as a yellow to orange crystalline powder that is virtually insoluble in water. Methotrexate was developed as a … Methotrexate: Drug Effects, Side Effects, Dosage and Uses
Products Vitamin A is commercially available in the form of pharmaceuticals, dietary supplements, foods, and cosmetics, among others. Dosage forms include, for example, capsules, tablets, effervescent tablets, syrups and eye ointments. Structure and properties Vitamin A is one of the fat-soluble vitamins and is practically insoluble in water. Vitamin A is the name given to … Vitamin A
Indications Hyperlipidemia Agents Colestyramine (Quantalan) Colestipol (Colestid) Sodium polystyrene sulfonate (Resonium A) for the treatment of hyperkalemia. Resina polystyrenolica anionica fortis (Ipocol).
Cholerstinester storage disease is a lysosomal storage disease and inborn error of metabolism with a genetic basis. The disease is hereditary and is caused by a genetic mutation in the coding genes for lysosomal acid lipase. Symptomatic treatment of patients is conservative medication or enzyme replacement therapy steps. What is cholesterol ester storage disease? The … Cholesterol Ester Storage Disease: Causes, Symptoms & Treatment
Colestyramine is an active ingredient used in the treatment of hypercholesterolemia. Too high LDL cholesterol levels in the blood can increase the risk of arteriosclerosis and thus of heart attacks and similar diseases. Colestyramine binds the bile acids in the intestines and prevents their reabsorption into the body. As a result, the body needs more … Colestyramine
