Temozolomide

Products Temozolomide is commercially available as capsules and as a powder for the preparation of an infusion solution (Temodal, generics). It has been approved in many countries since 1999. Structure and properties Temozolomide (C6H6N6O2, Mr = 194.2 g/mol) is an imidazotetrazine derivative. It is a prodrug that is biotransformed by hydrolysis to the active metabolite … Temozolomide

Melanoma Causes and Treatment

Symptoms Melanomas are discolored, growing, skin lesions that arise from pigmented moles in about 30% of cases. They are found primarily on the skin, but can occur anywhere melanocytes are found, including the oral mucosa, respiratory tract, or eye, for example. In men they are most common on the upper body, in women on the … Melanoma Causes and Treatment

Dacarbazine

Products Dacarbazine is commercially available as a lyophilizate in lancing ampoules (Dacin). It has been approved in many countries since 2004. Structure and properties Dacarbazine (C6H10N6O, Mr = 182.2 g/mol) is present as a colorless to ivory colored substance. It is an imidazole carboxamide derivative. Dacarbazine is a prodrug that is biotransformed in the body … Dacarbazine