Cystitis: Inflammation of the Bladder

Symptoms Acute, uncomplicated bladder infections are among the most common infectious diseases in women. A bladder infection is considered uncomplicated or simple when the urinary tract is functionally and structurally normal and there are no diseases that promote infection, for example, diabetes mellitus or immunosuppression. Symptoms include: Painful, frequent and difficult urination. Strong urge to … Cystitis: Inflammation of the Bladder

Anastrozole

Products Anastrozole is commercially available in the form of film-coated tablets (Arimidex, generic). It has been approved in many countries since 1996. Structure and properties Anastrozole (C17H19N5, Mr = 293.4 g/mol) exists as a white powder that is very sparingly soluble in water. It is a triazole derivative with a non-steroidal structure. Effects Anastrozole (ATC … Anastrozole

Androgenetic Alopecia in Women

Symptoms Increasing diffuse thinning of the hair occurs in the area of the middle parting. In this case, unlike androgenetic alopecia in men, not all hair is lost, but the scalp becomes visible over time. Often, a densely hairy strip remains frontally above the forehead. Dense hair is also still found on the sides and … Androgenetic Alopecia in Women

Gynecologics

Active ingredients (selection) Progestins Estrogens Herbal gynecologics Monk’s pepper Black cohosh

Conjugated Estrogens

Products Conjugated estrogens have been approved in many countries since 2015 in fixed combination with bazedoxifene (Duavive). Other preparations, such as Premarin and Premella, are off-label in many countries. Other products are available in other countries, such as the United States. Structure and properties Unlike other drugs, conjugated estrogens do not contain a single defined … Conjugated Estrogens

Vaginal Flora

Vaginal flora and vaginal health Vaginal flora or vaginal microflora refers to the natural colonization of the vagina with microorganisms. One of the most important species involved is the lactobacilli, also known as lactic acid bacteria or Döderlein bacteria. Species observed include, for example , , and . They convert glycogen to lactic acid, providing … Vaginal Flora

Vaginal Dryness: Causes and Treatment

Symptoms Possible symptoms include vulvovaginal dryness, itching, inflammation, burning, feeling of pressure, discharge, light bleeding, pain during sexual intercourse, and local infectious disease. The urinary tract may be involved, manifested, for example, by frequent and painful urination, cystitis, blood in the urine, and urinary incontinence. Causes A common cause of symptoms is vaginal atrophy in … Vaginal Dryness: Causes and Treatment

Nucleic Acids

Structure and properties Nucleic acids are biomolecules found in all living things on Earth. A distinction is made between ribonucleic acid (RNA, RNA, ribonucleic acid) and deoxyribonucleic acid (DNA, DNA, deoxyribonucleic acid). Nucleic acids are polymers composed of so-called nucleotides. Each nucleotide consists of the following three units: Sugar (carbohydrate, monosaccharide, pentose): ribose in RNA, … Nucleic Acids

Estradiol

Products Estradiol is commercially available in tablet, transdermal patch, transdermal gel, vaginal ring, and vaginal tablet forms, among others. It is also combined fixed with progestogens. Structure and properties Estradiol (C18H24O2, Mr = Mr = 272.4 g/mol) exists as a white crystalline powder that is practically insoluble in water. Synthetic estradiol is bioidentical with human … Estradiol

GnRH Analogs

Products GnRH analogs are commercially available in many countries in the form of injectables, implants, and nasal sprays, among others. The first agent to be approved was goserelin (Zoladex) in 1990. Structure and properties GnRH analogs are synthetically produced derivatives of gonadotropin-releasing hormone (GnRH, LHRH) produced in the hypothalamus. GnRH is a decapeptide and has … GnRH Analogs

Triptorelin

Products Triptorelin is commercially available as an injectable. It has been approved in many countries since 1995. Structure and properties Triptorelin is a more potent derivative of gonadotropin-releasing hormone (GnRH). At position 6, the amino acid glycine has been replaced by D-tryptophan. It is a decapeptide. GnRH: Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly. Triptorelin: Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly Effects Triptorelin (ATC L02AE04) is … Triptorelin

Citalopram: Drug Effects, Side Effects, Dosage and Uses

Products Clomiphene was commercially available in tablet form (Serophene, Clomid). It was approved in many countries since 1967 and is currently no longer available. Drugs containing the active ingredient can be imported from abroad. Structure and properties Clomiphene (C26H28ClNO, Mr = 405.95 g/mol) is a nonsteroidal triphenylethylene derivative that exists as an unequal mixture of … Citalopram: Drug Effects, Side Effects, Dosage and Uses