Effects Fibrates (ATC C10AB) have lipid-lowering properties. They primarily lower elevated blood triglyceride levels and have a moderate effect on LDL cholesterol and slightly increase HDL. The effects are due to activation of nuclear receptors PPAR (mainly PPARα). Indications Blood lipid disorders, especially hypertriglyceridemia. Agents Bezafibrate (Cedur retard) Fenofibrate (Lipanthyl) Fenofibric acid (Trilipix) Gemfibrozil (Gevilon) … Fibrate
Products Etofibrate is commercially available in the form of sustained-release capsules (Lipo-Merz retard). The drug is no longer registered in many countries. Structure and properties Etofibrate (C18H18ClNO5, Mr = 363.8 g/mol is a diester of clofibric acid and nicotinic acid linked via ethylene glycol. Effects Etofibrate (ATC C10AB09) is lipid-lowering. It lowers elevated cholesterol and … Etofibrate
Etofibrate, like clofibrate, is a derivative of clofibric acid just like statins and nicotinic acids. In this context, they belong to the group of active substances known as lipid-lowering agents. Etofibrate is mainly effective in the case of an increased concentration of triglycerides. The lowering of cholesterol is less pronounced in this case. What is … Etofibrate: Effects, Uses & Risks
