Toceranib

Products Toceranib is commercially available in the form of film-coated tablets (Palladia). It is approved exclusively as a veterinary drug in many countries and has been since 2010. Structure and properties Toceranib (C22H25FN4O2, Mr = 396.5 g/mol) is present in drugs as the phosphate salt toceranib phosphate, a crystalline, yellow-orange powder. It has structural and … Toceranib

Tazarotene

Products Tazarotene was approved in many countries in 1998 and is now no longer available. Zorac is out of commerce. External products are available in the United States (eg, Tazorac). Structure and properties Tazarotene (C21H21NO2S, Mr = 351.5 g/mol) is a prodrug that is rapidly biotransformed in the body to the active carboxylate metabolite tazarotenic … Tazarotene

Alkaloids

Products Alkaloids and their derivatives are contained as active ingredients in numerous medicines. They have been used medicinally for thousands of years, such as opium with morphine or coca leaves with cocaine. In 1805, a pure alkaloid was extracted for the first time by the German pharmacist Friedrich Sertürner with morphine. Structure and properties Alkaloids … Alkaloids

Teriflunomide

Products Teriflunomide is commercially available in the form of film-coated tablets (Aubagio). It was approved in many countries in 2013. Teriflunomide can be taken perorally, unlike earlier MS medications, and does not need to be injected. Structure and properties Teriflunomide (C12H9F3N2O2, Mr = 270.2 g/mol) is the active metabolite of the prodrug leflunomide (Arava), which … Teriflunomide

Levothyroxine: Effects, Uses & Risks

Various hormonal diseases require hormonal adjustment or hormone replacement therapy. This also applies to thyroid disease. Thus, in the case of hypothyroidism, the administration of artificial thyroid hormones is necessary. Levothyroxine, for example, is used in this case. What is hypothyroidism? Levothyroxine is a thyroid hormone. More precisely, it is the T4 form of the … Levothyroxine: Effects, Uses & Risks

Acitretin

Products Acitretin is commercially available in capsule form (Neotigason, Acicutuan). It has been approved in many countries since 1990. Structure and properties Acitretin (C21H26O3, Mr = 326.4 g/mol) is an aromatic derivative of retinoic acid (= tretinoin). It is lipophilic and exists as a greenish yellow powder that is practically insoluble in water. Effects Acitretin … Acitretin

Ribavirin

Products Ribavirin is commercially available in the form of film-coated tablets (Copegus). It has been approved in many countries since 1990. Structure and properties Ribavirin (C8H12N4O5, Mr = 244.2 g/mol) is a purine nucleoside analog. It exists as a white crystalline powder that is readily soluble in water. In cells, the drug is biotransformed to … Ribavirin