Products Flavoxate is commercially available in the form of film-coated tablets (Urispas). It has been approved in many countries since 2008. Structure and properties Flavoxate (C24H25NO4, Mr = 391.5 g/mol) is present in drugs as flavoxate hydrochloride, an oxo-benzopyran and piperidine derivative. An active metabolite is involved in the effects. Effects Flavoxate (ATC G04BD02) has … Flavoxat
Products Flibanserin (Addyi) was approved in the United States in 2015 in the form of film-coated tablets. The drug has not yet been registered in many countries. Flibanserin was originally developed at Boehringer Ingelheim as an antidepressant. It was marketed in the United States by Sprout Pharmaceuticals. Structure and properties Flibanserin (C20H21F3N4O, Mr = 390.4 … Flibanserin
Products Naproxen has been approved in many countries since 1975 and is commercially available in the form of film-coated tablets (e.g., Apranax, Proxen, generics). Other dosage forms such as the suppositories and the juice are no longer available. Drugs with a deep dose have been available over the counter since 1999 (Aleve with 200 mg … Naproxen: Drug Effects, Side Effects, Dosage and Uses
Products Naratriptan is commercially available in the form of film-coated tablets (Naramig). It has been approved in many countries since 1997. Structure and properties Naratriptan (C17H25N3O2S, Mr = 335.5 g/mol) is structurally related to serotonin and is an indole and piperidine derivative. It is present in drugs as naratriptan hydrochloride, a white to slightly yellowish … Naratriptan: Drug Effects, Side Effects, Dosage and Uses
Products Linagliptin has been registered as a film-coated tablet in the United States and EU since 2011 and in many countries since 2012 (Trajenta). It went on sale in many countries on May 1, 2012. Linagliptin is also combined fixed with metformin as well as with empagliflozin. Trijardy XR is a fixed combination of empagliflozin, … Linagliptin
Products Afatinib was approved in the US and EU in 2013 and in many countries in 2014 in film-coated tablet form (Giotrif). Structure and properties Afatinib (C24H25ClFN5O3, Mr = 485.9 g/mol) is a 4-aniline quinazoline derivative that is present in drugs as afatinib dimaleate, a white to brownish-yellow powder that is soluble in water. It … Afatinib
Products The selective serotonin reuptake inhibitors (SSRIs) are mainly taken in the form of film-coated tablets or capsules. In addition, other dosage forms such as dispersible tablets, melting tablets and drops are available. Zimelidin was the first to be developed in the 1970s and was approved in the early 1980s. Sales had to be discontinued … Selective Serotonin Reuptake Inhibitor
Products The fixed combination of the neprilysin inhibitor sacubitril with valsartan was approved in the United States, the EU, and many countries in 2015 in the form of film-coated tablets (Entresto). The combination is also referred to as LCZ696. Structure and properties Sacubitril (C24H29NO5, Mr = 411.5 g/mol) is an ester prodrug that is hydrolyzed … Sacubitril
Products Safinamide is commercially available in the form of film-coated tablets (Xadago). It was approved in many countries and in the EU in 2015 and in the US in 2017. Structure and properties Safinamide (C17H19FN2O2, Mr = 302.3 g/mol) is an α-aminoamide derivative. Effects Safinamide (ATC N04BD03) has indirect dopaminergic properties. It is a selective … Safinamide
Products Clarithromycin is commercially available as film-coated tablets, sustained-release tablets, oral suspension, and powder for solution for infusion (Klacid, generics). It has been approved in many countries since 1990. Clarithromycin should not be confused with ciprofloxacin. Structure and properties Clarithromycin (C38H69NO13, Mr = 747.96 g/mol) exists as a white crystalline powder that is practically insoluble … Clarithromycin
