Products Zolmitriptan is commercially available as film-coated tablets, meltable tablets, and as a nasal spray (Zomig, generics). It has been approved in many countries since 1997. Generic versions entered the market in 2012. Structure and properties Zolmitriptan (C16H21N3O2, Mr = 287.4 g/mol) is an indole and oxazolidinone derivative structurally related to serotonin. It exists as … Zolmitriptan
Products Melatonin is commercially available in the form of sustained-release tablets (Circadin, Slenyto). It was approved as a prescription drug in the EU in 2007 and in many countries in 2009. Melatonin may also be included in magistral formulations. Slenyto was registered in many countries in 2019. In some countries – for example, the United … Melatonin: Drug Effects, Side Effects, Dosage and Uses
Products Melatonin receptor agonists are commercially available in tablet and capsule form. Structure and properties Melatonin receptor agonists are structurally derived from and related to the natural hormone melatonin. Effects Melatonin, a sleep hormone produced by the pineal (pineal) gland of the brain from tryptophan, has a central role in the body in regulating the … Melatonin Receptor Agonists
Fluvoxamine is an antidepressant that belongs to the group of selective serotonin reuptake inhibitors. In Germany, the active ingredient has been approved for the treatment of depression and obsessive-compulsive disorder, but it is also frequently used to treat anxiety and panic disorders and post-traumatic stress disorder. When using the drug, interactions with other medications such … Fluvoxamine: Effects, Uses & Risks
Agomelatine is sold in Germany under the name Valdoxan and has only been on the market for a few years. It is a melatonin receptor agonist, which is mainly used for mild to severe depression and can also combat chronic sleep disorders within a certain range. What is agomelatine? Agomelatine promotes the release of norepinephrine … Agomelatine: Effects, Uses & Risks
Products Clozapine is commercially available in tablet form (Leponex, generic). It has been approved in many countries since 1972. It is also known as Clozaril in some countries. Clozapine was developed at Wander and Sandoz. Structure and properties Clozapine (C18H19ClN4, Mr = 326.8 g/mol) exists as a yellow crystalline powder that is practically insoluble in … Clozapine
Products Fluvoxamine is commercially available in the form of film-coated tablets (Floxyfral). It has been approved in many countries since 1983. Structure and properties Fluvoxamine (C15H21F3N2O2, Mr = 318.33 g/mol) is present in drugs as fluvoxamine maleate, a white, odorless, crystalline powder that is sparingly soluble in water. Effects Fluvoxamine (ATC N06AB08) has antidepressant properties. … Fluvoxamine
Definition When two or more drugs are combined, they may affect each other. This is especially true with regard to their pharmacokinetics (ADME) and effects and adverse effects (pharmacodynamics). This phenomenon is called interaction and drug-drug interaction. Interactions are usually undesirable because they can lead to, for example, loss of efficacy, side effects, poisoning, hospitalization, … Interactions
Products Duloxetine is commercially available in the form of capsules (Cymbalta, generic). It has been approved in many countries since 2005. Structure and properties Duloxetine (C18H19NOS, Mr = 297.4 g/mol) is present in drugs as pure -duloxetine hydrochloride, a white to light brown powder that is sparingly soluble in water. Effects Duloxetine (ATC N06AX21) has … Duloxetine
Products Agomelatine is commercially available in the form of film-coated tablets (Valdoxan, generic). It was approved in the EU in 2009 and in many countries in 2010. Structure and properties Agomelatine (C15H17NO2, Mr = 243.30 g/mol) exists as a white powder that is practically insoluble in water. It is a naphthalene analog of the epiphyseal … Agomelatine
Products Tizanidine is commercially available in tablet and sustained-release capsule form (Sirdalud, Sirdalud MR, generics). It has been approved in many countries since 1983. Structure and properties Tizanidine (C9H8ClN5S, Mr = 253.7 g/mol) is present in drugs as tizanidine hydrochloride, a white crystalline powder that is somewhat soluble in water. It is an imidazoline and … Tizanidin
Products Rasagiline is commercially available in tablet form (Azilect). It has been approved in many countries since 2005. Generic versions were first released in 2015. Structure and properties Rasagiline (C12H13N, Mr = 171.24 g/mol) is an aminoindan derivative and has an asymmetric carbon atom. Therapeutic uses are found for the -enantiomer. It is present in … Rasagiline
