Products Ivacaftor was approved by the FDA and EMA in 2012 and by Swissmedic in 2014 in film-coated tablet form (Kalydeco). Also available is a fixed combination with lumacaftor (Orkambi). In 2016, a granule was also approved. In 2018, the combination with tezacaftor was approved in the US and EU (Symdeko, Symkevi). In 2020, a … Ivacaftor
Products Copovidone is found as an excipient in drugs, mainly in tablets. Not to be confused with crospovidone. Structure and properties Copovidone is a copolymer of 1-ethenylpyrrolidone-2-one and ethenyl acetate in the ratio 3:2 (m/m). It exists as a white to yellowish white hygroscopic powder or as a leaflet and is readily soluble in water. … Copovidone
Products Pharmacopeial grade pure silicon dioxide is available in pharmacies and drugstores. Note: In English, silicon is called silicon and silicon dioxide is called silicon dioxide. Structure and properties Silicon dioxide (SiO2, Mr = 60.08 g/mol) is the oxide of silicon. It exists, for example, as a fine white powder and is practically insoluble in … Silicon Dioxide
Products Antibiotics (singular: antibiotic) are commercially available in the form of tablets, dispersible tablets, capsules, as infusion preparations, suspensions and syrups for children, and as granules, among others. There are also some topical preparations, such as creams, ointments, eye drops, eye ointments, ear drops, nasal ointments and sore throat tablets. The first active ingredient from … Antibiotics: Antibacterial Drugs
Products Pantoprazole is commercially available in the form of enteric-coated tablets and has been approved in many countries since 1997 (Pantozol, generic). Less commonly used are the granules and the injectable. Structure and properties Pantoprazole (C16H15F2N3O4S, Mr = 383.37 g/mol) is a benzimidazole derivative and a racemate. In tablets, it is present as sodium salt … Pantoprazole
Products Paracetamol is commercially available in the form of tablets, film-coated tablets, melting tablets, effervescent tablets, as granules, drops, syrups, suppositories, soft capsules, and infusion solution, among others (e.g., Acetalgin, Dafalgan, Panadol, and Tylenol). Paracetamol was not approved until the 1950s (Panadol, Tylenol), although it was developed in the 19th century. It has been registered … Paracetamol: Drug Effects, Side Effects, Dosage and Uses
Products Mesalazine is commercially available as film-coated tablets, enteric-coated sustained-release tablets, granules, sustained-release granules, clysms, and suppositories (e.g., Asacol, Mezavant, Pentasa, Salofalk). It has been approved in many countries since 1984. Structure and properties Mesalazine (C7H7NO3, Mr = 153.1 g/mol) corresponds to 5-aminosalicylic acid (5-ASA). The active ingredient exists as powders or crystals that are … Mesalazine
Products Potassium sorbate is present in many drugs as an excipient, mainly in liquid and semi-solid dosage forms. Structure and properties Potassium sorbate (C6H7KO2, Mr = 150.2 g/mol) is the potassium salt of sorbic acid, a short-chain unsaturated fatty acid. It exists as a white, odorless powder or granules and is very soluble in water. … Potassium Sorbate
Products Methyl cellulose is found in pharmaceuticals as an excipient, for example in tablets. Structure and properties Methyl cellulose is a partially -methylated cellulose. It is a methyl ether. It exists as a white, yellowish-white to grayish-white powder that is hygroscopic when dried or as granules and is practically insoluble in hot water. Methyl cellulose … Methylcellulose
Products Granules (lat. : grain) are commercially available as pharmaceuticals, dietary supplements and medical devices. Structure and properties Granules are preparations composed of solid and dry grains, each grain being a porous agglomerate of powder particles with sufficient strength to allow different handling. The production process is called granulation (pelletizing). It can be built up … Granules
Products Esomeprazole is commercially available as tablets, film-coated tablets, granules for oral suspension, and injectables (Nexium, generics). It has been approved in many countries since 2000. Generics entered the market in 2012. Fixed combinations: Naproxen and esomeprazole (Vimovo, 2011). Acetylsalicylic acid and esomeprazole (Axanum, 2012), not commercially available. Structure and properties Esomeprazole (C17H19N3O3S, Mr = … Esomeprazole
Products Arabic gum (gum arabic) is available in pharmacies and drugstores as an open product. It is also found in foods, medicines and in cosmetics. Gum arabic was used by the ancient Egyptians over 4000 years ago. Structure and properties Arabic gum is an air-hardened, gummy exudate that comes out naturally or after cutting the … Arabic Gum
