Products Entecavir is commercially available as film-coated tablets and as an oral solution (Baraclude). It has been approved in many countries since 2006. Generic versions have been available since 2017. Structure and properties Entecavir (C12H15N5O3, Mr = 277.3 g/mol) is a 2′-deoxyguanosine nucleoside analog. It exists as a white powder that is sparingly soluble in … Entecavir
Products Bisoprolol is commercially available in film-coated tablet form as a monopreparation (Concor, generic) and as a fixed combination with hydrochlorothiazide (Concor plus, generic). It has been approved in many countries since 1986. In 2016, a fixed combination with perindopril was approved (Cosyrel). Structure and properties Bisoprolol (C18H31NO4, Mr = 325.4 g/mol) is present in … Bisoprolol Effects and Side Effects
Products Sulfadiazine is commercially available in combination with silver as silver sulfadiazine cream and gauze (Flammazine, Ialugen plus). This article refers to internal use. See also under silver sulfadiazine. Structure and properties Sulfadiazine (C10H10N4O2S, Mr =250.3 g/mol) exists as in the form of crystals or as a crystalline powder with white, yellowish or light pink … Sulfadiazine
Products Retigabine was approved in many countries as film-coated tablets since 2011 (Trobalt). In the United States, it is referred to as ezogabine. It was discontinued in 2017. Structure Retigabine (C16H18FN3O2, Mr = 303.3 g/mol) is a carbamate that was developed starting from the analgesic flupirtine. The free primary amino group is -glucuronidated (see below). … Retigabine (Ezogabine)
Products The fixed combination Deanxit with the two active ingredients melitracene and flupentixol is commercially available in many countries in the form of film-coated tablets. The drug has been approved since 1973, initially as dragées. The marketing authorization holder is the Danish company Lundbeck. Structure and properties The active ingredients are present in the drug … Melitracene and Flupentixol
Products Somatropin is commercially available as an injectable from several manufacturers. Recombinant growth hormone has been available since the late 1980s. Biosimilars are approved in some countries. Structure and properties Somatropin is a recombinant polypeptide hormone with a molecular mass of 22 kDa, consisting of 191 amino acids. It corresponds to human growth hormone from … Somatropin
Products Carmellose is commercially available in the form of eye drops and as an oral spray (e.g., Cellufluid, Glandosane, Optava). Structure and properties Carmellose is the calcium or sodium salt of a partially -carboxymethylated cellulose (carboxymethylcellulose calcium or carboxymethylcellulose sodium). Effects Carmellose (ATC S01XA20) forms an optically clear film on the eye, which approximates natural … Carmellose
Products Hydrous alumina is commercially available in combination with magnesium hydroxide as a suspension and in the form of chewable tablets (Alucol). It has been approved in many countries since 1957. Structure and properties Alumina (Al2O3, Mr = 102.0 g/mol) is the oxide of aluminum. Hydrous alumina, as defined by the pharmacopoeia, contains 47 to … Alumina
Structure and properties Aluminum sulfate (Al2(SO4)3 – x H2O) exists as colorless, lustrous crystals or as a crystalline mass. It dissolves readily in hot water. Effects Aluminum sulfate has antiseptic and astringent properties. Fields of application Aluminum sulfate is a component of acetic-tartaric alumina solution, which is commercially available, among other things, in the form … Aluminum Sulfate
Products Soothing ointment PH can be made in well-equipped pharmacies. Retailers can also obtain it from specialized suppliers such as Hänseler. Structure and properties Soothing ointment is a soft, slightly yellowish ointment. It should be stored tightly closed, protected from light. Depending on the prescription, storage in the refrigerator is also recommended. Preparation Bleached wax … Soothing Ointment
Products Orbifloxacin was commercially available in the form of film-coated tablets for animals (Orbax, out of commerce in many countries), among other products. It is also used as a combination preparation in the form of ear drops (Posatex). Structure and properties Orbifloxacin (C19H20F3N3O3, Mr = 395.4 g/mol) is a fluoroquinolone. Effects Orbifloxacin (ATCvet QJ01MA95) has … Orbifloxacin
Active ingredients Drugs are in development but not yet on the market in many countries Cannabis, dronabinol
