Products Zafirlukast was commercially available in the form of film-coated tablets (Accolate, off label). It was approved in many countries in 1998. It was discontinued from distribution in 2019. Montelukast is a suitable substitute. Structure and properties Zafirlukast (C31H33N3O6S, Mr = 575.7 g/mol) exists as a fine, white to pale yellow, amorphous powder that is … Zafirlukast
Products LSD (lysergic acid diethylamide) is one of the banned narcotics in many countries and is therefore no longer legally available. Exemption permits may be issued. Structure and properties LSD (C20H25N3O, Mr = 323.4 g/mol) was first synthesized in 1938 by Swiss chemist Albert Hofmann at Sandoz, with the aim of producing an analeptic. He … LSD
Products Umifenovir is available in Russia, among other countries, in tablet, capsule, and syrup form without a doctor’s prescription (Arbidol). It was developed in the Soviet Union in the 1970s. The drug is not approved in the United States, Europe, and Switzerland. Structure and properties Umifenovir (C22H25BrN2O3S, Mr = 477.4 g/mol) is a brominated indole … Umifenovir
Products Fluvastatin is commercially available in the form of capsules and sustained-release generic tablets (generics). It has been approved in many countries since 1993. Sales of the original Lescol were discontinued by Novartis in 2018. Structure and properties Fluvastatin (C24H26FNO4, Mr = 411.5 g/mol) is present in drugs as fluvastatin sodium, a white or pale … Fluvastatin
Products Dimethyltryptamine is not commercially available in many countries. It is one of the banned narcotics. Structure and properties DMT or ,-dimethyltryptamine (C12H16N2, Mr = 188.3 g/mol) is structurally related to serotonin. It is an indole derivative found in the secretion of toad and in various plants (e.g. ). DMT is an important ingredient in … DMT (Dimethyltryptamine)
Products Frovatriptan is commercially available in the form of film-coated tablets (Menamig). It has been approved in many countries since 2004. Structure and properties Frovatriptan (C14H17N3O, Mr = 243.3 g/mol) is present in drugs as frovatriptan succinate monohydrate, a white powder that is soluble in water. It is an indole derivative and structurally related to … Frovatriptan
Products Pindolol was commercially available in tablet form (Visken). It had been approved in many countries since 1969. Furthermore, a fixed combination with clopamide was available (Viskaldix). Structure and properties Pindolol (C14H20N2O2, Mr = 248.3 g/mol) is an indole derivative and a racemate. It exists as a white crystalline powder that is practically insoluble in … Pindolol
Products Tezacaftor was approved in the US and EU in 2018 and in many countries in 2019 in fixed combination with previously registered ivacaftor in film-coated tablet form (Symdeko). In 2020, a fixed combination with tezacaftor, elexacaftor, and ivacaftor was approved (Trikafta). Structure and properties Tezacaftor (C26H27F3N2O6, Mr = 520.5 g/mol) exists as a white … Tezacaftor
