Effects Reverse transcriptase inhibitors (ATC J05AF) have antiviral properties against HIV. The effects are due to inhibition of the viral enzyme reverse transcriptase, which transcribes viral RNA into DNA and is important for viral replication. Structure and properties Within the drug group, two distinct classes are distinguished. The so-called nucleoside reverse transcriptase inhibitors, abbreviated NRTIs, … Reverse Transcriptase Inhibitors (HIV)
Most common mechanism of action Most drugs bind to a macromolecular target structure called a drug target. These are usually proteins such as receptors, transporters, channels, and enzymes, or nucleic acids. For example, opioids interact with endogenous opioid receptors to relieve pain. Targets can also be exogenous structures. Penicillins inhibit bacterial enzymes responsible for building … Mechanism of Action
Ranitic® is a partially prescription drug containing Ranitidine as the active ingredient. The drug is a histamine H2-receptor blocker and is prescribed for symptoms such as heartburn. Ranitic® is available in film-coated tablets containing either 75mg, 150mg, or 300mg Ranitidine. Prescription is only required for those packages containing 150mg or 300mg of the active ingredient … Ranitic®
Contraindications Ranitic® should not be taken if there is a known allergy to the active ingredient Ranitidine. Even if hypersensitivity reactions to drugs with similar active substances as Ranitidine are known, a physician should be consulted regarding the use of Ranitic. Since the active substance contained in Ranitic® can trigger an acute porphyria attack, the … Contraindications | Ranitic®
Side effects As with all medicines, Ranitic® can cause side effects. Overall, however, the drug is considered to be well tolerated. The most common side effects reported are those that affect the acute state of health. These include frequent fatigue, nausea, dizziness, diarrhea, constipation and skin rash. Occasionally, liver values in the blood count may … Side effects | Ranitic®
Introduction The so-called serotonin noradrenaline reuptake inhibitors (SNRI) are mainly drugs used in the treatment of depression. The most important active ingredients in this class of drugs are venlafaxine and duloxetine. The name refers to the ability of these drugs to exert their effect on both serotonin and noradrenalin levels in the central nervous system. … SNRI
Effect of SNRI As described above and as can be seen from the name, serotonin noradrenalin reuptake inhibitors (SNRI) inhibit the reuptake of serotonin and noradrenalin into the nerve cells. In order to understand this mechanism, one should consider the structure of a synapse, i.e. an interconnection point between two nerve cells. A synapse consists … Effect of SNRI | SNRI
When should SNRI not be given? SNRIs must not be used if an intolerance and allergic reaction to the active substance has occurred. The use of so-called MAOIs, the irreversible monoamine oxidase inhibitors, is also considered a strict contraindication.These are drugs used to treat depression or Parkinson’s disease. If taken at the same time or … When should SNRI not be given? | SNRI
SNRI during pregnancy Pregnancy and antidepressants are two closely interwoven topics, as numerous studies have shown that the incidence of depression is significantly higher among pregnant women and women in the puerperium than in the general population. The most important piece of advice regarding pregnancy during depression treatment is to tell your doctor that you … SNRI during pregnancy | SNRI
What should be considered when weaning? Patients treated with SNRI should not discontinue or change the dose without consulting their doctor. SNRI should never be stopped suddenly. This can lead to life-threatening side effects. These include symptoms such as fatigue, dizziness, headache, drowsiness or confusion, diarrhea, nausea, nervousness, agitation, or discomfort. Seizures are also possible … What should be considered when weaning? | SNRI
