Products On the one hand, fibrinogen is commercially available in the form of injection and infusion preparations. On the other hand, products for local treatment are also available, usually containing additional clotting factors (thrombin and possibly factor VIII). Structure and properties Fibrinogen is a glycoprotein that circulates in blood plasma. The Pharmacopoeia defines human fibrinogen … Fibrinogen
Products Remifentanil is commercially available as a powder for the preparation of a concentrate for solution for injection or infusion (Ultiva, generic). It has been approved in many countries since 1996. Structure and properties Remifentanil (C20H28N2O5, Mr = 376.4 g/mol) is present in drugs as remifentanil hydrochloride, a white powder. The drug is rapidly hydrolyzed … Remifentanil
Products Janus kinase inhibitors are commercially available in the form of tablets and capsules with different galenics. Structure and properties The structure of Janus kinase inhibitors is characterized by nitrogen heterocycles, which are often condensed. Effects The agents have selective immunosuppressive, anti-inflammatory, and antiproliferative properties. The effects are based on inhibition of Janus kinases (JAK). … Janus Kinase Inhibitors
Risperdal® Consta® is a preparation from the group of atypical neuroleptics with the active ingredient risperidone. It is available in powder and solution form and is used to prepare a soluble suspension for intramuscular injection. Thanks to a special preparation of the active ingredient, Risperdal® Consta® is a long-term neuroleptic with a duration of action … Risperdal Consta
Contraindications Risperdal® Consta® must not be given in cases of hyperprolactinaemia, i.e. when there are elevated levels of the hormone prolactin in the blood. This excess of prolactin can be caused by a tumor of the pituitary gland (so-called prolactinoma). Particular caution is advised when taking Risperdal® Consta® in patients with Parkinson’s disease and severe … Contraindications | Risperdal Consta
Products Interferon alfa-2b was commercially available as a drug for injection or infusion (Intron-A). It was approved in many countries as of 1998. In other countries, the drug remains available. Structure and properties Interferon alfa-2b is a recombinant, water-soluble protein obtained from a -strain by biotechnological methods. It consists of 165 amino acids and has … Interferon Alfa-2B
Products Proton pump inhibitors (PPIs) are commercially available in many countries in the form of film-coated tablets, MUPS tablets, capsules, as granules for preparation of an oral suspension, and as injectable and infusion preparations. The first active ingredient from this group to be approved in many countries was omeprazole (Antra, Losec), developed by Astra in … Proton Pump Inhibitors
Products Paliperidone is commercially available as sustained-release tablets (Invega, generic) and as a sustained-release suspension for intramuscular injection (Xeplion, Trevicta, generic). It has been approved in many countries since 2008. Structure and properties Paliperidone (C23H27FN4O3, Mr = 426.5 g/mol) exists as a racemate and is practically insoluble in water. It belongs to the group of … Paliperidone
Products Enzymes are commercially available as drugs in the form of tablets, lozenges, capsules, as well as injection and infusion preparations, among others. Many products are subject to prescription, but there are also some agents which are released for the OTC market. Structure and properties Therapeutic enzymes are usually proteins, i.e. polymers of amino acids, … Therapeutic Enzymes
Products Etomidate is commercially available as an emulsion for injection (etomidate lipuro). It has been approved in many countries since 1993. Structure and properties Etomidate (C14H16N2O2, Mr = 244.3 g/mol) is a pure -enantiomer. The imidazole-5-carboxylate ester is present as a white powder that is very sparingly soluble in water. Effects Etomidate (ATC N01AX07) has … Etomidate
Definition Lipotalon® is a drug from the group of glucocorticoids. Like all glucocorticoids, to whose group cortisone also belongs, Lipotalon® has a strong anti-inflammatory effect. It contains the active ingredient dexamethasone and is used for injection into joints for local action. Indication Lipotalon® can be used in inflammatory processes of the joints such as inflammatory … Lipotalon
Ampoules Lipotalon® is available in so-called ampoules, which are filled with the injection solution. Each ampoule of Lipotalon® contains 1 ml of the solution. The active ingredient in the solution is called dexamethasone and is contained in the solution in 4 mg amounts. The other components of the solution consist of water, soybean oil, fats, … Ampoules | Lipotalon
