The syringe is one of the most well-known medical instruments. Among other things, it is used to administer injections. What is a syringe? A disposable syringe is a syringe that receives sterile packaging and is used only once. With the help of a syringe, liquid medications can be administered by injection. These agents are also … Syringe: Applications & Health Benefits
The medical profession refers to a biochemical metabolization process in the first liver passage as the first-pass effect, which deforms drugs taken perorally into so-called metabolites and thus either attenuates or activates their efficacy. The intensity of metabolization in the liver is directly related to personal liver functions and thus may differ from patient to … First-pass Effect: Treatment, Effect & Risks
Products Daptomycin is commercially available as a powder for the preparation of a solution for injection or infusion (Cubicin). It has been approved in many countries since 2007. Generic versions are registered. Structure and properties Daptomycin (C72H101N17O26, Mr = 1620.7 g/mol) is a cyclic lipopeptide that is obtained as a fermentation product from . It … Daptomycin
Products Penicillins are commercially available today in the form of film-coated tablets, capsules, as solutions for injection and infusion, as powders for preparing an oral suspension, and as syrups, among others. Penicillin was discovered in September 1928 at St. Mary’s Hospital in London by Alexander Fleming. He was working with staphylococcal cultures in Petri dishes. … Penicillins
Products Caplacizumab was approved in many countries in 2019 as a powder and solvent for solution for injection (Cablivi). Structure and properties Caplacizumab is a humanized, bivalent nanobody (single-domain antibody) produced by biotechnological methods. It consists of two building blocks (PMP12A2hum1) linked by a 3-alanine linker. Effects Caplacizumab (ATC B01AX07) binds to the A1 domain … Caplacizumab
Products Pegfilgrastim is commercially available as a solution for injection in the form of prefilled syringes (Neulasta). It has been approved in many countries since 2003. Biosimilars have been approved. Structure and properties Pegfilgrastim is a conjugate of filgrastim with a single 20-kDa polyethylene glycol (PEG) molecule. Filgrastim is a protein of 175 amino acids … Pegfilgrastim
Products Vedolizumab was approved in many countries in 2015 as a powder for a concentrate for the preparation of an infusion solution (Entyvio). In 2020, a prefilled pen and prefilled syringe were also registered. Structure and properties Vedolizumab is a humanized IgG1 monoclonal antibody with a molecular mass of 147 kDa. Effects Vedolizumab (ATC L04AA33) … Vedolizumab
Products Amikacin is commercially available as a solution for injection (Amikin). It has been approved in many countries since 1976. Structure and properties Amikacin (C22H43N5O13, Mr = 585.6 g/mol) is semisynthetically prepared from kanamycin A. It is found in drugs as amikacin sulfate, a white powder that is readily soluble in water. Effects Amikacin (ATC … Amikacin
Products Lenograstim is commercially available as an injection/infusion preparation (Granocyte). It has been approved in many countries since 1993. Structure and properties Lenograstim is a protein of 174 amino acids produced by biotechnology. The sequence corresponds to human granulocyte colony-stimulating factor (G-CSF). Unlike filgrastim, lenograstim is identical to G-CSF and is glycosylated. Effects Lenograstim (ATC … Lenograstim
Products Meropenem is commercially available as a powder for solution for injection/infusion (Meronem, generic). It has been approved in many countries since 1995. The antibiotic is also combined with the beta-lactamase inhibitor vaborbactam. Structure and properties Meropenem (C17H25N3O5S, Mr = 383.5 g/mol) is present in drugs as meropenem trihydrate, a white to slightly yellowish crystalline … Meropenem
A cannula represents a hollow needle used as part of a syringe to penetrate human or animal tissue to inject or withdraw fluids. In medicine, it is used for diagnostic and therapeutic purposes. Needles are now almost exclusively used only once for routine procedures for hygienic reasons. What is a cannula? Cannulas are hollow needles … Cannula: Applications & Health Benefits
Products Methylprednisolone is commercially available as an ointment, fatty ointment, cream, in tablet form, and as an injection and infusion preparation (e.g., Medrol, generics). Structure and properties Methylprednisolone (C22H30O5, Mr = 374.5 g/mol) Effects Methylprednisolone (ATC D07AA01, ATC D10AA02, ATC H02AB04) is anti-inflammatory, antiallergic, and immunosuppressive.
