Products Zonisamide is commercially available in the form of capsules (Zonegran). It has been approved in many countries since 2006. Structure and properties Zonisamide (C8H8N2O3S, Mr = 212.2 g/mol) is a benzisoxazole derivative and a sulfonamide. It exists as a white powder that is soluble in water. Effects Zonisamide (ATC N03AX15) has anticonvulsant and antiepileptic … Zonisamide
Products Quetiapine is commercially available in the form of film-coated tablets and sustained-release tablets (Seroquel / XR, generic, auto-generic). It has been approved in many countries since 1999. Generics of film-coated tablets entered the market in 2012, and generics of sustained-release tablets were first registered in 2013. Structure and properties Quetiapine (C21H25N3O2S, Mr = 383.5 … Quetiapine
Products Gammahydroxybutyrate is commercially available as an oral solution (Xyrem). It has been approved in many countries since 2006. The drug belongs to narcotics and requires an aggravated prescription. GHB is also known to be manufactured and trafficked illegally. Structure and properties The free γ-hydroxybutyric acid (C4H8O3, Mr = 104.1 g/mol) is a colorless and … Gamma Hydroxybutyrate (GHB)
Products Lofexidine was approved in the United States in 2018 in film-coated tablet form (Lucemyra). In the United Kingdom, the agent was approved for the treatment of opioid withdrawal back in the early 1990s (UK: BritLofex). Structure and properties Lofexidine (C11H12Cl2N2O, Mr = 259.1 g/mol) is present in the drug as lofexidine hydrochloride, a white … Lofexidine
Products Prazosin is commercially available in some countries in tablet form. It is no longer approved in many countries. Structure and properties Prazosin (C19H21N5O4, Mr = 383.4 g/mol) is a quinazoline derivative. It is present in drugs as prazosin hydrochloride, a white crystalline substance that is sparingly soluble in water. Effects Prazosin (ATC C02CA01) is … Prazosin
Products Felbamate is commercially available in tablet and suspension form (Taloxa). It has been approved in many countries since 1997. Structure and properties Felbamate (C11H14N2O4, Mr = 238.2 g/mol) is a dicarbamate. It exists as a white crystalline powder with a typical odor that is sparingly soluble in water. Effects Felbamate (ATC N03AX10) has antiepileptic … Felbamate
Products Metformin is commercially available in many countries in the form of film-coated tablets and has been available since 1960. In addition to the original Glucophage, numerous generics are available today. Metformin is often combined with various other antidiabetic drugs fix. It has been used medically since 1957. Other antidiabetic biguanides such as phenformin and … Metformin: Drug Effects, Side Effects, Dosage and Uses
Products Varenicline is commercially available in the form of film-coated tablets (Champix, in some countries: Chantix). It has been approved in many countries since 2006 and has been reimbursable under certain conditions since July 1, 2013. Full reimbursement details can be found in the Specialty List under Limitations. Structure and properties Varenicline (C13H13N3, Mr = … Varenicline
Products Nortriptyline was commercially available in the form of film-coated tablets (nortrilen). It was approved in many countries in 1964. It was discontinued from distribution in 2016. Structure and properties Nortriptyline (C19H21N, Mr = 263.4 g/mol) is present in drugs as nortriptyline hydrochloride, a white powder that is sparingly soluble in water. It is an … Nortriptyline
Products Antiepileptic drugs are commercially available in the form of tablets, dispersible tablets, capsules, solutions, suspensions, syrups, as nasal sprays, enemas, and as injectables, among others. Structure and properties The antiepileptic drugs are structurally heterogeneous agents. Within the class, several groups can be identified (see below). Effects The agents have antiepileptic, anticonvulsant, and muscle relaxant … Antiepileptic Drugs
Products Mesuximide is commercially available in the form of capsules (Petinutin). It has been approved in many countries since 1963. Structure and properties Mesuximide (C12H13NO2, Mr = 203.2 g/mol) belongs to the succinimides and exists as a racemate. The active metabolite -demethylmesuximide, with a long half-life of over 30 hours, is also involved in the … Mesuximide
Products Eslicarbazepine has been approved in tablet form in the EU since 2009, in the United States since 2013, and in many countries in 2020 (Zebinix, Aptiom). Structure and properties Eslicarbazepine (C15H14N2O2, Mr = 254.3 g/mol) is present in drugs in the form of the prodrug eslicarbazepine acetate, which is hydrolyzed in the body after … Eslicarbazepine