Products Interferon alfa-2a is commercially available as an injectable (Roferon-A). It has been approved in many countries since 1997. Structure and properties Interferon alfa-2a is a recombinant protein obtained from a -strain by biotechnological methods. It consists of 165 amino acids and has a molecular mass of approximately 19 kDa. Effects Interferon alfa-2a (ATC L03AB04) … Interferon Alfa-2A
Products Interferon alfa-2b was commercially available as a drug for injection or infusion (Intron-A). It was approved in many countries as of 1998. In other countries, the drug remains available. Structure and properties Interferon alfa-2b is a recombinant, water-soluble protein obtained from a -strain by biotechnological methods. It consists of 165 amino acids and has … Interferon Alfa-2B
Products Interferon beta-1a is commercially available as a solution for injection (Avonex, Rebif). It has been approved in many countries since 1997. Structure and properties Interferon beta-1a is a recombinant protein biotechnologically derived from CHO cells. It consists of 166 amino acids, has the same amino acid sequence as natural interferon beta, and is glycosylated … Interferon Beta-1A
Products Interferon beta-1b is commercially available as a powder and solvent for the preparation of a solution for injection (Betaferon). It has been approved in many countries since 1995. Structure and properties Interferon beta-1b is a recombinant protein of 165 amino acids with a molecular mass of approximately 18,500 Da. It is derived from an … Interferon Beta-1B
Products Therapeutic proteins are usually administered in the form of injection and infusion preparations and must be stored in a refrigerator. The first recombinant protein to be approved was human insulin in 1982. Some proteins, for example, are also available in tablet, capsule, and powder form and can be stored at room temperature, such as … Therapeutic Proteins
Products Ropeginterferon alfa-2b was approved as a solution for injection in many countries in 2020 (Besremi). Structure and properties Ropeginterferon alfa-2b is a recombinant interferon alfa-2b linked to a two-arm methoxypolyethylene glycol (mPEG). It has a molecular mass of approximately 60 kDa and is produced by biotechnological methods. Effects Ropeginterferon alfa-2b (ATC L03AB15) inhibits proliferation … Ropeginterferon Alfa-2B
Products Imiquimod is commercially available as a cream in single-use sachets (Aldara 5%). It has been approved in many countries since 1999. Since 2014, a preparation containing 3.75% imiquimod has also been registered in many countries (Zyclara). Structure and properties Imiquimod (C14H16N4, Mr = 240.3 g/mol) is an imidazoquinoline amine structurally similar to nucleoside analogs … Imiquimod: Drug Effects, Side Effects, Dosage and Uses
Killer cells are part of the immune system. As so-called cytotoxic T cells (acquired immune system) or as natural killer cells (innate immune system), they recognize and attack cells foreign to the body and altered cells belonging to the body, such as cancer cells, cells infected by viruses or bacteria, or aging cells. The killer … Killer Cell: Structure, Function & Diseases
Symptoms Atopic dermatitis, or neurodermatitis, is a noncontagious, chronic inflammatory skin disease that causes episodes of red, rough, dry or weeping, crusted and scaly skin. Eczema can occur all over the body and is typically accompanied by severe itching. Patients have dry skin. In infants, the disease begins on the scalp and cheeks. Depending on … Atopic Dermatitis: Eczema