Symptoms Drug-induced prolongation of the QT interval can rarely lead to severe arrhythmias. This is polymorphic ventricular tachycardia, known as torsade de pointes arrhythmia. It can be seen on the ECG as a wave-like structure. Due to the dysfunction, the heart cannot maintain blood pressure and can only pump insufficient blood and oxygen to the … Prolongation of the QT Interval
Products Abiraterone is commercially available in the form of film-coated tablets (Zytiga). It has been approved in many countries since 2011. Structure and properties Abiraterone acetate (C26H33NO2, Mr = 391.5 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a prodrug and is rapidly biotransformed in the body to … Abiraterone Acetate
Products Solifenacin is commercially available in the form of film-coated tablets (Vesicare, generics). It has been approved in many countries since 2006. Structure and properties Solifenacin (C23H26N2O2, Mr = 362.5 g/mol) is a tertiary amine and a phenylquinoline derivative that has structural similarities to atropine. It is present in drugs as (1)-(3)-solifenacin succinate, a white … Solifenacin
Products Shampoos are marketed as drugs, personal care products, and medical devices. Examples of active ingredients in medicines are listed below: Glucocorticoids Selenium disulfide, sulfur Antifungals: Ketoconazole, ciclopirox Zinc pyrithione Salicylic acid Structure and properties Shampoos are liquid to viscous preparations for application to the skin and scalp, which are washed out with water after … Shampoos
Products Antacids are commercially available in the form of lozenges, chewable tablets, as a powder, and as a gel (suspension) for oral use, among others. Well-known brands in many countries include Rennie, Alucol, and Riopan. The first medicines were developed as early as the 19th century. Structure and properties The drugs contain active ingredients that … Antacids to Neutralise Stomach Acid
Products Caffeine citrate solution was newly approved in many countries in 2016 (Peyona). It was available earlier in other countries. Structure and properties Caffeine (C8H10N4O2, Mr = 194.2 g/mol) exists as a white crystalline powder or as white silk-like crystals and is sparingly soluble in water. The substance sublimes readily. Citric acid monohydrate (C6H8O7 – … Caffeine Citrate Solution
Products Olodaterol was approved in many countries in 2014 as a solution for inhalation (Striverdi). In 2016, a fixed-dose combination with tiotropium bromide was also marketed (Spiolto). Both drugs are administered with the Respimat. Respimat The Respimat is a new inhalation device that releases a visible spray, or aerosol. The droplets are fine and move … Olodaterol
Products Omeprazole is commercially available in tablet, capsule, and injection/infusion forms and has been approved in many countries since 1988. In addition to the original Antramups, generics and the -enantiomer esomeprazole (Nexium) are also commercially available. At the end of March 2010, after pantoprazole, omeprazole was also approved for self-medication in many countries. In the … Omeprazole: Drug Effects, Side Effects, Dosage and Uses
Products and approval Fingolimod is commercially available in capsule form (Gilenya) and has been approved in many countries since 2011. First generic products were registered in 2020 and entered the market in 2021. Fingolimod was the first specific multiple sclerosis drug to be administered orally, rather than being injected subcutaneously or as an infusion. In … Fingolimod
Products Ketoconazole has been approved in many countries since 1981 and is now only commercially available as a shampoo and as a cream for external treatment (Nizoral, generics). Nizoral tablets were taken off the market in 2012 due to declining demand. This article refers to external use. Structure and properties Ketoconazole (C26H28Cl2N4O4, Mr = 531.4 … Ketoconazole
Symptoms Oral thrush is an infection of the mouth and throat with Candida fungi. Different manifestations are distinguished. The actual oral thrush is usually called acute pseudomembranous candidiasis. The leading symptom is the white to yellowish, small-spotted, partially intermingled coating of the mucous membranes in the mouth and throat area. It consists of epithelial cells, … Oral Thrush
Symptoms Acute, uncomplicated vaginal mycosis occurs more frequently in women of childbearing age. In contrast, it is rare in girls and postmenopausal women. About 75% of all women contract vaginal mycosis once in their lives. The clinical manifestation varies. Possible symptoms include: Itching and burning (leading symptoms). Inflammation of the vagina and vulva with symptoms … Vaginal Fungus
