Products Amsacrine is commercially available as an infusion preparation (Amsidyl). It has been approved in many countries since 1993. Structure and properties Amsacrine (C21H19N3O3S, Mr = 393.5 g/mol) is an aminoacridine derivative. Effects Amsacrine (ATC L01XX01) has antineoplastic properties. The effects are due to inhibition of topoisomerase II. As a result, DNA synthesis is blocked. … Amsacrine
Products Sulfites are added to pharmaceuticals, foods and personal care products as excipients and additives. They can also be naturally present in foods. Even the Romans used sulfur dioxide as a preservative for wine. Structure and properties Sulfites are the salts of sulfurous acid, which is extremely unstable and undetectable in water (H2SO3). Example sodium … Sulfites
Symptoms Fatigue is a physiological and subjective response of the organism to mental and physical exertion. It is undesirable when it occurs rapidly, frequently, and excessively. Fatigue manifests itself, among other things, in a lack of energy, exhaustion, weakness, listlessness, and reduced performance and motivation. It can also be accompanied by irritability. Fatigue occurs acutely … Fatigue
Products Pethidine is commercially available as a solution for injection. It has been approved in many countries since 1947. The drug is subject to strict control as a narcotic and is available only by prescription. Structure and properties Pethidine (C15H21NO2, Mr = 247.3 g/mol) is a phenylpiperidine derivative. In pharmaceuticals, it is present as pethidine … Pethidine
Products Most sartans are commercially available as tablets or film-coated tablets. Losartan was the first agent approved in many countries in 1994 (Cosaar, USA: 1995, Cozaar). Sartans are often combined with hydrochlorothiazide fix. The name of the drug group is derived from the suffix -sartan of the active ingredients. The drugs are also called angiotensin … Sartans
Products Carprofen is commercially available in the form of tablets, chewable tablets, and as a solution for injection. It has been approved in many countries since 1998. Structure and properties Carprofen (C15H12ClNO2, Mr = 273.7 g/mol) is an arylpropionic acid derivative. It exists as a white crystalline powder that is practically insoluble in water. Carprofen … Carprofen
Products Carteolol is available in the form of extended-release eye drops (Arteoptic LA). Carteolol has been approved in many countries since 1984. Arteopilo, the combination with pilocarpine, is no longer marketed in many countries. Structure and properties Carteolol (C16H24N2O3, Mr = 292.4 g/mol) is a dihydroquinolinone and a racemate. It is present in drugs as … Carteolol
Products Carvedilol is commercially available in tablet form (Dilatrend, generic). It has been approved in many countries since 1995. Carvedilol is also combined with ivabradine fixed (Carivalan). Structure and properties Carvedilol (C24H26N2O4, Mr = 406.5 g/mol) is a racemate, with both enantiomers participating in the pharmacological effects. It exists as a white crystalline powder that … Carvedilol
Products Thiopental is commercially available as an injectable (generic). It has been approved in many countries since 1947. Structure and properties Thiopental (C11H18N2O2S, Mr = 242.3 g/mol) is present in the drug as thiopental sodium, a yellowish white, hygroscopic powder that is readily soluble in water. It is a lipophilic thiobarbiturate identical to pentobarbital except … Thiopental
Products Codeine is available alone or in combination with other active ingredients in the form of tablets, effervescent tablets, capsules, dragées, syrups, drops, bronchial pastilles, and as suppositories. It is also combined fixedly with acetaminophen for the treatment of pain (see under codeine acetaminophen). Structure and properties Codeine (C18H21NO3, Mr = 299.36 g/mol) is -methylated … Codeine: Drug Effects, Side Effects, Dosage and Uses
Products Sympathomimetics are commercially available, for example, in the form of tablets, capsules, granules, injectable solutions, eye drops, and nasal sprays. Structure and properties Sympathomimetics are structurally derived from the natural neurotransmitters epinephrine and norepinephrine. Effects Sympathomimetics have sympathomimetic properties, meaning that they promote the effects of the sympathetic nervous system, a portion of the … Sympathomimetics
Products Tadalafil is commercially available in the form of film-coated tablets (Cialis, Adcirca, generics). It has been approved in many countries since 2004. Generics were registered in 2016 and came on the market in 2019. This article is related to erectile dysfunction treatment. Structure and properties Tadalafil (C22H19N3O4, Mr = 389.4 g/mol) exists as a … Tadalafil