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Synonyms in a broader sense Wegener’s disease, allergic angiitis and granulomatosis, Klinger-Wegener-Churg syndrome, Wegener’s granulomatosis, Wegener-Klinger-Churg giant cell granuloarteritis, rhinogenic granulomatosis Definition Wegner’s granulomatosis is a disease in which the small blood vessels become inflamed throughout the body (systemic vasculitis). This leads to the formation of tissue nodules (granulomas). Mostly the ears, airways, lungs and … Wegener’s granulomatosis

Therapy At the beginning of Wegener’s granulomatosis the antibiotic Clotrimazol (broad-spectrum antibiotics with the ingredients: Trimethroprim and Sulfamethoxazole), e.g. available as Cotrim®, which leads to an improvement, although the mode of action is still completely unclear. In the further course of the disease, treatment is usually with cortisone (trade names e.g. Prednisolon®, Prednihexal®, Decortin®). This … Therapy | Wegener’s granulomatosis

Complications Wegner’s granulomatosis can lead to permanent damage, such as hearing loss, unilateral blindness, limited kidney function. It can also lead to changes in the shape of the nose due to the frequent inflammations and thus to the formation of a saddle nose. All articles in this series: Wegener’s granulomatosis Therapy Complications