Products Disulfiram is commercially available in the form of water-suspendable tablets called dispersible tablets (Antabus). It has been approved in many countries since 1949. Structure and properties Disulfiram or tetraethylthiuram disulfide (C10H20N2S4, Mr = 296.54 g/mol) is a white to almost white crystalline powder that is practically insoluble in water. Prior to its medical use, … Disulfiram
Symptoms In women, trichomoniasis manifests as inflammation of the vaginal mucosa with redness, swelling, and a frothy, thin, yellowish-green, foul-smelling discharge. The urethra and cervix may also be infected. The type of discharge varies. In addition, there may be itching, small skin bleeding, and pain during sexual intercourse and urination. In men, the disease is … Trichomoniasis
Symptoms Rosacea is a chronic inflammatory skin disorder of the face that typically affects the cheeks, nose, chin, and central forehead symmetrically (Figure). The skin around the eyes is left out. It occurs more often in people with fair skin and in middle age, but it can occur in any skin type and at any … Rosacea Causes and Treatment
Definition Pseudomembranous colitis is a serious inflammation of the colon mucosa. It is caused by the bacterium Clostridium difficile and usually occurs in conjunction with previous antibiotic therapy. Untreated, pseudomembranous colitis can be fatal. The main symptom of this disease is massive watery diarrhea, which can contain blood. EpidemiologyFrequency Exact figures on the contamination rate … Pseudomembranous colitis
Symptoms of pseudomembranous colitis The symptoms of pseudomembranous colitis range from mild diarrhea, which limits itself after some time, to a severe feeling of illness with massive watery, bloody diarrhea and fever. In addition, the affected patients complain of severe abdominal pain and abdominal cramps. However, the symptoms are not directly related to the severity … Symptoms of pseudomembranous colitis | Pseudomembranous colitis
Therapy If pseudomembranous colitis is related to antibiotic therapy, it should be discontinued immediately. In some cases this is already sufficient. The natural intestinal flora can develop again after stopping the therapy and curbs the spread of Clostridium difficile. In severe cases, a fluid and electrolyte supply is usually essential. This often has to be … Therapy | Pseudomembranous colitis
Prophylaxis The most important thing to protect against pseudomembranous colitis is a healthy intestinal flora.This provides natural protection against attacking bacteria. Probiotic preparations can be used for this purpose. These support a healthy intestinal flora, even under difficult conditions. Studies have shown that a regular intake of yoghurt improves the intestinal flora and thus prevents … Prophylaxis | Pseudomembranous colitis
Effect Nitroimidazoles are antibacterial (bactericidal) and antiparasitic. They are reduced under anaerobic conditions to cytotoxic metabolites that covalently bind to and damage DNA. The damage may take the form of loss of helical structure, impaired matrix function, or strand breaks, leading to inhibition of DNA synthesis. Indications Spectrum: gram-positive and gram-negative anaerobic bacteria and some … Nitroimidazole
Main representative The main representative of nitromidazoles is metromidazole. Classification This substance belongs to the group of nitroimidazoles. Besides metronidazole, the drugs tinidazole and nimorazole belong to this rather small group of substances. Metronidazole is also known under the trade name ClontR. It is a standard and collaborative drug in the treatment of anaerobic infections. … Metronidazole and other nitromidazoles
Interactions As mentioned above, metronidazole should not be combined with alcohol due to intolerance development. If the drugs barbiturates and phenytoin are administered at the same time, a faster degradation of metronidazole and a resulting reduction in the effect must be expected due to an enzyme acceleration. If blood thinners (anticoagulants) are combined with metronidazole, … Interactions | Metronidazole and other nitromidazoles
Introduction Clont® is the trade name for the antibiotic metronidazole. Mode of action Like any antibiotic, it damages certain bacteria. The effect of Clont® depends on the absence of oxygen: it can only have a damaging effect on the DNA of cells if there is no oxygen in the environment. Therefore, it only works on … Clont®
Symptoms A change in urine color is manifested by a deviation from the normal color of urine, which usually varies from pale yellow to amber. It may occur as a solitary sign or along with other symptoms. Urine is usually clear and not cloudy. It gets its color from urine pigments called urochromes. These are, … Change in Urine Color