Background Bilirubin is the lipophilic breakdown product of heme, which is responsible for oxygen transport in erythrocytes. It is bound to albumin in plasma and is glucuronidated in the liver by the UDP-glucuronosyltransferase UGT1A1 and excreted in bile. Conjugated bilirubin is more hydrophilic than lipophilic unconjugated bilirubin and can be eliminated from the body. Symptoms … Neonatal Jaundice Causes and Treatment
Rhesus incompatibility, colloquially known as blood group incompatibility, primarily affects pregnant women and their unborn children in their second pregnancy. In the case of rhesus incompatibility, the rhesus factor in the mother’s blood does not match that of the unborn child, which can lead to significant health complications for the baby. During regular screening examinations … Rh Incompatibility: Causes, Symptoms & Treatment
Course of disease Icterus is a symptom of an illness or, in the context of newborns, usually a naturally occurring phenomenon. The course of the “jaundice triggering” disease is basically decisive. Depending on the cause and therapeutic measures, the course of the icterus is also determined. Decisive for the existence of jaundice are increased concentrations … Course of disease | Jaundice
What is a kernicterus? Kerincterus is a severe damage to the child’s brain caused by abnormally high concentrations of bilirubin or indirect bilirubin. Indirect bilirubin has not yet been processed in the liver and, due to its special property, can cross the so-called blood–brain barrier. Various diseases can cause an unusually high increase in bilirubin … What is a kernicterus? | Jaundice
Synonyms Icterus Definition jaundice Jaundice is an unnatural yellowing of the skin or the conjunctiva of the eyes and the mucous membranes, which is caused by an increase in the metabolic product bilirubin. If the level of bilirubin in the body rises above 2 mg/dl, yellowing is triggered. What is an icterus? Icterus is the … Jaundice
Symptoms of jaundice The icterus is characterized by a coloration of the skin. Often the skin tone is described as yellowish, which is also reflected in the name of jaundice. If the total bilirubin rises above 2mg/dl in the serum, not only the skin but also the eyes can be affected by the coloration. This … Symptoms of jaundice | Jaundice
Frequency of jaundice The frequency of jaundice depends on the disease causing it. In hepatitis A, for example, less than 10% of children under 6 years of age have an icteric course, 45% of children over 6 years of age and 75% of adults. Hemolyticus neonatorum disease as the cause of jaundice (icterus) is relatively … Frequency of jaundice | Jaundice
Introduction Neonatal jaundice – also called neonatal icterus or Icterus neonatorum (ancient Greek ikteros = jaundice) – describes the appearance of yellowing of the skin and sclera of the eyes (“sclerae”) of newborns. This yellow coloration is caused by deposits of the decomposition products of the red blood pigment (hemoglobin). The degradation product responsible for … Neonatal jaundice
Symptoms Often – depending on the severity of the jaundice – there is only a visible yellowing of the skin and the sclerae of the newborn without any further symptoms. The yellowing itself is not noticeable to the offspring. This is usually the case with physiological, harmless neonatal jaundice. If, however, for various reasons, massive … Symptoms | Neonatal jaundice
ConsequencesLate consequences A physiological, harmless newborn icterus of light to medium intensity usually heals on its own without any consequences. Therefore, there are no (late) consequences. However, if the bilirubin concentration in the blood exceeds a certain threshold value (Icterus gravis = more than 20 mg/dl), there is a risk that the bilirubin will “cross … ConsequencesLate consequences | Neonatal jaundice
Infantile sputum (meconium) is the name given to the first stool of a newborn baby, which is greenish-black in color. Usually babies excrete it within 12 to 48 hours, but for some the excretion occurs in the womb, which can lead to a condition called meconium aspiration syndrome. What is puerperal meconium? Infantile saliva or … Kindspech
What is phototherapy? Phototherapy is a branch of the so-called physical therapy. Here the patient is irradiated with blue light. This rather short-wave light transfers its energy to the irradiated skin and can thus develop its therapeutic effect. Phototherapy is most frequently used for newborns, but it can also be used for various skin diseases. … Phototherapy
