Reverse Transcriptase Inhibitors (HIV)

Effects Reverse transcriptase inhibitors (ATC J05AF) have antiviral properties against HIV. The effects are due to inhibition of the viral enzyme reverse transcriptase, which transcribes viral RNA into DNA and is important for viral replication. Structure and properties Within the drug group, two distinct classes are distinguished. The so-called nucleoside reverse transcriptase inhibitors, abbreviated NRTIs, … Reverse Transcriptase Inhibitors (HIV)

Nevirapine

Products Nevirapine is commercially available in tablet and sustained-release tablet form (Viramune, generics). It has been approved in many countries since 1997. Structure and properties Nevirapine (C15H14N4O, Mr = 266.3 g/mol) exists as a white crystalline powder that is practically insoluble in water. It has a non-nucleoside structure. Effects Nevirapine (ATC J05AG01) has antiviral properties … Nevirapine