Zika Fever

Symptoms Possible symptoms of Zika fever include fever, feeling sick, a rash, muscle and joint pain, headache, and conjunctivitis. The illness is usually benign and lasts a few days to a week (2 to 7 days). An asymptomatic course is common. Guillain-Barré syndrome may rarely occur as a complication. If a pregnant woman is infected, … Zika Fever

Frostbite

Symptoms In localized frostbite, the skin becomes pale, cold, hard, and insensitive to touch and pain. Only when it warms and thaws does redness appear and severe, pulsating pain, burning, and tingling set in. In addition, edema and blisters may form and, in a severe course, tissue dies. Often affected are exposed parts of the … Frostbite

Azilsartan

Products Azilsartan has been approved in the United States and the EU in tablet form since 2011 (Edarbi). In many countries, it was registered in August 2012 as the 8th member of the sartan drug group. In 2014, a fixed combination with chlortalidone was approved (Edarbyclor). Structure Azilsartan (C25H20N4O5, Mr = 456.5 g/mol) is present … Azilsartan

Quinapril

Products Quinapril is commercially available in the form of film-coated tablets as a monopreparation (Accupro) and as a fixed combination with hydrochlorothiazide (Accuretic, Quiril comp). It has been approved in many countries since 1989. Generic versions are registered. Structure and properties Quinapril (C25H30N2O5, Mr = 438.5 g/mol) is present in drugs as quinapril hydrochloride, a … Quinapril

Misoprostol

Products Misoprostol tablets for medication abortion were approved in many countries in 2015 (MisoOne). This article refers to abortion. In addition, other drugs exist with other indications (gastric protection, induction of labor). Structure and properties Misoprostol (C22H38O5, Mr = 382.5 g/mol) is a synthetic derivative of prostaglandin E1 and exists as a mixture of two … Misoprostol

Indometacin

Products Indometacin is commercially available as sustained-release capsules, indometacin eye drops (Indophtal), and solution for application (Elmetacin). This article refers to oral administration. The sustained-release capsules have been on the market in many countries since 1995 (Indocid, generic). Structure and properties Indomethacin (C19H16ClNO4, Mr = 357.8 g/mol) is an indoleacetic acid derivative. It exists as … Indometacin

Indomethacin Eye Drops

Products Indometacin has been approved in many countries since 1999 in the form of eye drops (Indophtal, Indophtal UD). Structure and properties Indomethacin (C19H16ClNO4, Mr = 357.8 g/mol) is an indoleacetic acid derivative. It exists as a white to yellow crystalline powder that is practically insoluble in water. Effects Indomethacin (ATC S01BC01) has analgesic and … Indomethacin Eye Drops

Aceclofenac

Products Aceclofenac is approved in Germany, among other countries, in the form of film-coated tablets (Beofenac). It is not registered in many countries. Structure and properties Aceclofenac (C16H13Cl2NO4, Mr = 354.2 g/mol) is structurally related to diclofenac and is partially metabolized to it. It exists as a white crystalline powder that is practically insoluble in … Aceclofenac

Cortisone Tablets Effects and Side Effects

Products Cortisone tablets are medicinal products which are intended for ingestion and contain active substances from the group of glucocorticoids. The tablets, water-soluble tablets and sustained-release tablets are usually monopreparations, which are often divisible. Glucocorticoids were first used medicinally in the late 1940s. Structure and properties The glucocorticoids contained in the drugs are derived from … Cortisone Tablets Effects and Side Effects

Enterohepatic Circulation

Definition Pharmaceutical agents are excreted primarily in the urine and, via the liver, in the bile in the stool. When excreted via the bile, they re-enter the small intestine, where they may be reabsorbed. They are transported back to the liver via the portal vein. This repetitive process is called the enterohepatic circulation. It prolongs … Enterohepatic Circulation

Nabumetone

Products Nabumetone was commercially available in many countries in the form of film-coated tablets and soluble tablets (Balmox). It was approved in 1992 and went out of commerce in 2013, presumably for commercial reasons. Structure and properties Nabumetone (C15H16O2, Mr = 228.3 g/mol) exists as a white crystalline powder that is practically insoluble in water. … Nabumetone

Nadroparin

Products Nadroparin is commercially available as a solution for injection (Fraxiparine, Fraxiforte). It has been approved in many countries since 1988. Structure and properties Nadroparin is present in the drug as nadroparin calcium. It is the calcium salt of a low-molecular-weight heparin obtained by depolymerization of heparin from the intestinal mucosa of pigs using nitrous … Nadroparin