Products Entecavir is commercially available as film-coated tablets and as an oral solution (Baraclude). It has been approved in many countries since 2006. Generic versions have been available since 2017. Structure and properties Entecavir (C12H15N5O3, Mr = 277.3 g/mol) is a 2′-deoxyguanosine nucleoside analog. It exists as a white powder that is sparingly soluble in … Entecavir
Products 5-Fluorouracil is commercially available as an ointment (Efudix), as a topical solution in combination with salicylic acid (Verrumal), and in preparations for parenteral administration. This article refers to topical application. In 2011, 5-fluorouracil at the lower concentration of 0.5% was approved in many countries with Actikerall. Structure and properties 5-Fluorouracil (C4H3FN2O2, Mr = 130.08 … 5-Fluorouracil
Symptoms After the initial clinical manifestation in the form of chickenpox, the virus remains in a latent stage in the dorsal root ganglia for life. Reactivation of the virus occurs particularly in the presence of weakened immune defenses. Vesicles with cloudy contents form in the area supplied by the infected nerve, e.g. on the trunk … Shingles: Causes, Symptoms, Treatment, Prevention
Symptoms Symptoms of Covid-19 include (selection): Fever Cough (irritating cough or with sputum) Respiratory disorders, shortness of breath, shortness of breath. Feeling sick, fatigue Cold symptoms: runny nose, stuffy nose, sore throat. Pain in the limbs, muscle and joint pain. Gastrointestinal complaints: Diarrhea, nausea, vomiting, abdominal pain. Nervous system: impairment of the sense of smell … COVID-19
Symptoms Oral thrush, or primary gingivostomatitis herpetica, occurs primarily in children between 6 months and 5 years of age and in young adults around 20 years of age and may also affect older adults. It manifests itself in the following symptoms, among others: Swollen cervical lymph nodes, aphthoid lesions and ulcerations in the mouth and … Mouth Rot
Products Valaciclovir is commercially available in the form of film-coated tablets (Valtrex, generic). It has been approved in many countries since 1995. Structure and properties Valaciclovir (C13H20N6O4, Mr = 324.3 g/mol) is the ester of the natural amino acid valine and the antiviral drug aciclovir. It is present in drugs as valaciclovir hydrochloride, a white … Valaciclovir
Products Valganciclovir is commercially available in the form of film-coated tablets (Valcyte). It has been approved in many countries since 2001. Generic versions were registered in 2014. Structure and properties Valganciclovir (C14H22N6O5, Mr = 354.4 g/mol) is an L-valine ester prodrug of ganciclovir and is present in the drug product as valganciclovir hydrochloride, a white … Valganciclovir
Products Direct antiviralia are commercially available as drugs in the form of tablets, capsules, solutions, and creams, among others. The first antiviral agent was approved in the 1960s (idoxuridine). Structure and properties Antivirala are a large group of drugs and have no uniform chemical structure. However, groups can be formed, such as the nucleoside analogs. … Antiviralia
Products Penciclovir is commercially available as a cream and tinted cream (Fenivir). It has been approved in many countries since 1997. Famvir cream is out of commerce. Structure and properties Penciclovir (C10H15N5O3, Mr = 253.3 g/mol) is a mimetic of the DNA building block 2′-deoxyguanosine and is structurally related to aciclovir. It exists as a … Penciclovir
Structure and properties Nucleic acids are biomolecules found in all living things on Earth. A distinction is made between ribonucleic acid (RNA, RNA, ribonucleic acid) and deoxyribonucleic acid (DNA, DNA, deoxyribonucleic acid). Nucleic acids are polymers composed of so-called nucleotides. Each nucleotide consists of the following three units: Sugar (carbohydrate, monosaccharide, pentose): ribose in RNA, … Nucleic Acids
Products Brivudine is commercially available in tablet form (Brivex). It has been approved in many countries since 2003. It was originally developed in the German Democratic Republic. Structure and properties Brivudine (C11H13BrN2O5, Mr = 333.1 g/mol) is a nucleoside analog related to thymidine. Effects Brivudine (ATC J05AB) has antiviral properties against herpes viruses. It inhibits … Brivudine
Products Cidofovir was initially marketed in many countries as an infusion concentrate under the brand name Vistide (Gilead). It was approved in many countries in 1997 and had not been available since 2014. In 2017, a concentrate for the preparation of an infusion solution was approved (Sidovis). Structure and properties Cidofovir (C8H14N3O6P, Mr = 279.2 … Cidofovir
