Products Several drugs are commercially available as enteric-coated tablets. Listed below are active ingredients that are administered with this dosage form: Proton pump inhibitors such as pantoprazole and esomeprazole. Some painkillers, e.g., NSAIDs such as diclofenac Digestive enzymes: pancreatin Laxative: bisacodyl Salicylates: mesalazine, acetylsalicylic acid 100 mg. Structure and properties Enteric coated tablets belong to … Enteric-Coated Tablets
Definition and properties The administration or application of a drug refers to its use on the body. The dosage forms (drug forms) used for this purpose consist of the active ingredients and excipients. These include, for example, tablets, capsules, solutions, syrups, injectables, creams, ointments, eye drops, ear drops, and suppositories. Drugs can be liquid, semi-solid, … Administration
Products Etomidate is commercially available as an emulsion for injection (etomidate lipuro). It has been approved in many countries since 1993. Structure and properties Etomidate (C14H16N2O2, Mr = 244.3 g/mol) is a pure -enantiomer. The imidazole-5-carboxylate ester is present as a white powder that is very sparingly soluble in water. Effects Etomidate (ATC N01AX07) has … Etomidate
Products Direct oral anticoagulants (abbreviation: DOAKs) are commercially available in the form of film-coated tablets and capsules. By definition, they are oral drugs. Some representatives of the corresponding drug groups are also available as infusion preparations. Rivaroxaban (Xarelto) and dabigatran (Pradaxa) were the first active ingredients to be approved in 2008. The DOAKs were developed … DOAK
Products Direct factor Xa inhibitors are commercially available in the form of film-coated tablets and capsules. In 2008, rivaroxaban (Xarelto) was the first agent in this group to be approved in many countries and in the EU. Today, there are other drugs on the market, which are listed below. Like thrombin inhibitors, these active ingredients … Factor Xa Inhibitors
Products Betrixaban was approved in the United States in 2017 in capsule form (Bevyxxa). The drug has not yet been approved in the EU (Dexxience). Structure and properties Betrixaban (C23H22ClN5O3, Mr = 451.9 g/mol) is present in the drug as betrixaban maleate. It is a pyridine and anthranilamide derivative. Effects Betrixaban has antithrombotic properties. The … Betrixaban
Products Dupilumab was approved as a solution for injection in the United States and EU in 2017 and in many countries in 2019 (Dupixent). Structure and properties Dupilumab is a human recombinant IgG4 monoclonal antibody with a molecular mass of 147 kDa. It is produced by biotechnological methods. Effects Dupilumab (ATC D11AH05) has anti-inflammatory and … Dupilumab
Products Indacaterol is commercially available as hard capsules with a powder for inhalation (Onbrez Breezhaler) and has been approved since 2010. It is also combined fixed with the LAMA glycopyrronium bromide (Ultibro Breezhaler, approved 2014). The fixed combination with mometasone furoate (Atectura Breezhaler) was registered for asthma therapy in 2020. Finally, a combination of indacaterol … Indacaterol
Products Rocuronium bromide is commercially available as a solution for injection (esmeron, generic). It was approved in the United States in 1994 and in many countries in 1995. Structure and properties Rocuronium bromide (C32H53BrN2O4, Mr = 609.7 g/mol) exists as a nearly white to pale yellow, slightly hygroscopic powder that is readily soluble in water. … Rocuronium Bromide
Definition After a drug is ingested, it passes through the esophagus into the stomach and into the small intestine. There, the active ingredient must first be released from the dosage form. This is the prerequisite for it to be absorbed into the bloodstream via the cells of the mucosa. The dosage form thus exerts a … Release (Liberation)
