Rivaroxaban

Products Rivaroxaban is commercially available in the form of film-coated tablets (Xarelto, Xarelto vascular). It was approved in 2008 as the first agent in the direct factor Xa inhibitor group. Low-dose Xarelto vascular, 2.5 mg, was registered in many countries in 2019. Structure and properties Rivaroxaban (C19H18ClN3O5S, Mr = 435.9 g/mol) is a pure -enantiomer … Rivaroxaban

Colestyramine: Drug Effects, Side Effects, Dosage and Uses

Products Colestyramine is commercially available as a powder in sachets (Quantalan). It has been approved in many countries since 1990. Structure and properties Colestyramine is a strongly basic anion exchange resin in the chloride form, consisting of a styrene-divinylbenzene copolymer with quaternary ammonium groups. It exists as a white, fine, hygroscopic powder that is insoluble … Colestyramine: Drug Effects, Side Effects, Dosage and Uses

Tramadol: Drug Effects, Side Effects, Dosage and Uses

Products Tramadol is commercially available in the form of tablets, capsules, melting tablets, drops, effervescent tablets, suppositories, and as a solution for injection. (Tramal, generic). Fixed combinations with acetaminophen are also available (Zaldiar, generic). Tramadol was developed by Grünenthal in Germany in 1962 and has been approved in many countries since 1977 and in the … Tramadol: Drug Effects, Side Effects, Dosage and Uses

Antithrombotics

Effects Antithrombotic Anticoagulant Fibrinolytic Active ingredients Salicylates: Acetylsalicylic acid 100 mg (Aspirin Cardio). P2Y12 antagonists: Clopidogrel (Plavix, generics). Prasugrel (Efient) Ticagrelor (Brilique) GP IIb/IIIa antagonists: Abciximab (ReoPro) Eptifibatide (Integrilin) Tirofiban (Aggrastat) PAR-1 antagonists: Vorapaxar (Zontivity) Vitamin K antagonists (coumarins): Phenprocoumon (Marcoumar). Acenocoumarol (Sintrom) Not on sale in many countries: dicoumarol, warfarin. Heparins: Heparin sodium Heparin-Calcium … Antithrombotics

Bleeding in the Eye

Symptoms Bleeding in the eye manifests as bright red and painless spots between the conjunctiva and sclera of the eyeball. They usually occur unilaterally and are not accompanied by visual disturbances or inflammation. Mild irritation may occur. The entire conjunctiva may also be hypophagic (hyposphagma). Causes Hemorrhage occurs as a result of damage to blood … Bleeding in the Eye

Pelargonium Sidoides

Products Umckaloabo drops, film-coated tablets Kaloba (drops, film-coated tablets) is the co-marketing drug of Umckaloabo. It is exactly the same as Umckaloabo except for the packaging, but is subject to cash (SL). Umckaloabo syrup, Kaloba syrup, approval in 2020. Homeopathic mother tinctures and homeopathics, drops. Preparations with Stem plant Capeland Pelargonium DC (Geraniaceae) is a … Pelargonium Sidoides

Bruise (Hematoma) Symptoms and Causes

Symptoms Possible symptoms of a bruise (technical term: hematoma) include swelling, pain, inflammation, and discoloration of the skin that changes (red, blue, purple, green, yellow, brown) during the healing process. This text refers to simple and small-surface complaints that can be considered for self-medication. Causes The cause of a hematoma is blood leaking from injured … Bruise (Hematoma) Symptoms and Causes

Noscapine

Products Noscapine is commercially available in the form of lozenges, capsules, drops, as a syrup, and as suppositories. Except for Tussanil N, the drugs are combination products. Structure and properties The phthalideisoquinoline noscapine (C22H23NO7, Mr = 413.4 g/mol) is present in drugs as a free base or as noscapine hydrochloride monohydrate. Noscapine is a white … Noscapine

Goji

Products Goji berries and corresponding preparations such as capsules, juices or cosmetics are available from various suppliers, including pharmacies, drugstores and health food stores. Goji is an artificial word of recent origin, which is derived from the Chinese name. The berries belong to the so-called superfoods. Stem plants The berries come from two plants: Common … Goji

Sildenafil

Products Sildenafil is commercially available in the form of film-coated tablets and as a solution for injection (Viagra, Revatio, generics). It has been approved in many countries since 1998. Generics went on sale July 22, 2013, and the patent expired June 21. Pfizer launched auto-generic sildenafil Pfizer, identical to the original, back in May. In … Sildenafil

Interactions

Definition When two or more drugs are combined, they may affect each other. This is especially true with regard to their pharmacokinetics (ADME) and effects and adverse effects (pharmacodynamics). This phenomenon is called interaction and drug-drug interaction. Interactions are usually undesirable because they can lead to, for example, loss of efficacy, side effects, poisoning, hospitalization, … Interactions

Ginseng Health Benefits

Products Preparations containing ginseng are commercially available in the form of capsules, juice, and lozenges, among others. Ginseng is included in registered drugs and in dietary supplements. In East Asia and Southeast Asia, ginseng has been used medicinally for thousands of years. Stem plant C.A. Meyer, of the Araliaceae family, is native to Manchuria in … Ginseng Health Benefits