Physostigmine: Effects, uses, side effects

How physostigmine works Physostigmine stimulates the activity of the parasympathetic nervous system. This part of the autonomic nervous system is involved in controlling the internal organs, heartbeat, breathing and digestion. Physostigmine is a so-called cholinesterase inhibitor. It blocks the enzyme acetylcholinesterase, which breaks down the neurotransmitter acetylcholine. Acetylcholine is an important signaling substance of the … Physostigmine: Effects, uses, side effects

Physostigmine

Products There are no drugs containing physostigmine on the market in many countries. Structure and properties Physostigmine (C15H21N3O2, Mr = 275.3 g/mol) Stem Fabaceae. Effects Physostigmine is indirectly parasympathomimetic by inhibiting acetylcholinesterase; see under cholinesterase inhibitors. Indications Alzheimer’s disease As a miotic Antidote to curare poisoning and parasympatholytics, e.g., atropine.

Procaine: Drug Effects, Side Effects, Dosage and Uses

Products Procaine has been commercially available in many countries since 1941 in the form of ear drops (Otalgan). Currently, it is available in many countries only as a combination preparation. Structure and properties Procaine (C13H20N2O2, Mr = 236.31 g/mol) was synthesized as the first synthetic ester local anesthetic by Einhorn in 1905. The local anesthetic … Procaine: Drug Effects, Side Effects, Dosage and Uses

VX

Structure and properties VX (C11H26NO2PS, Mr = 267.4 g/mol) belongs to the group of organophosphates. It exists at room temperature as a slightly yellowish, oily, odorless and tasteless liquid with a high viscosity. The “V” stands for venom. The boiling point is relatively high at about 300°C. Therefore, VX is usually used as a liquid, … VX

Parasympathomimetics

Products Parasympathomimetics are commercially available in the form of tablets, capsules, solutions, transdermal patches, injectable solutions, and eye drops, among others. Structure and properties Many parasympathomimetics are structurally related to the natural ligand acetylcholine. Effects Parasympathomimetics have cholinergic (parasympathomimetic) properties. They promote the effects of the parasympathetic nervous system, a portion of the autonomic nervous … Parasympathomimetics

Datura Poisoning

Symptoms The possible symptoms and consequences of datura poisoning include: Dry mouth, dry skin and mucous membranes, thirst, difficulty speaking and swallowing. Dilation of the pupils Visual disturbances, sensitivity to light Urinary retention, constipation, nausea and vomiting. Feeling of heat, increased temperature, flush Rapid pulse, palpitations, low blood pressure. Movement disorders, rapid breathing rate Hallucinations … Datura Poisoning

Crabs

The crab louse (Latin Phthirus pubis) is a parasite that prefers to settle in the pubic hair area of humans. The infestation by crabs is medically also called pediculosis pubis. The parasite is about 1.0-1.5 mm long and has a broad, grey body. Therefore it is visible to the naked eye. At the end of … Crabs

Historical | Crabs

Historical It is assumed that the crab louse was first transmitted from apes to human ancestors about 3.3 million years ago. This was presumably due to the hunting of gorillas, contact with their environment, and their fur. According to studies, human crabs and gorilla crabs have the same ancestor before they developed independently. This led … Historical | Crabs

Which drugs slow down the pupil reflex? | Which medications or drugs affect the pupil?

Which drugs slow down the pupil reflex? When smoking weed, cannabis is inhaled, i.e. forms of cannabis such as grass, weed or marijuana are burned, so that the vapors can then be inhaled. This initially leads to a relaxing effect as well as euphoria and possibly hallucinogenic effects. This is followed by an increased appetite … Which drugs slow down the pupil reflex? | Which medications or drugs affect the pupil?