Products Medicines containing zipeprol are no longer on the market in many countries. Mirsol is no longer available. Zipeprol is classified as a narcotic. Structure and properties Zipeprol (C23H32N2O3, Mr = 384.5 g/mol) is a disubstituted piperazine derivative with a non-opioid structure. Effects Zipeprol (ATC R05DB15) has antitussive properties. In addition, anticholinergic, antihistamine, local anesthetic, … Zipeprol
Products Quetiapine is commercially available in the form of film-coated tablets and sustained-release tablets (Seroquel / XR, generic, auto-generic). It has been approved in many countries since 1999. Generics of film-coated tablets entered the market in 2012, and generics of sustained-release tablets were first registered in 2013. Structure and properties Quetiapine (C21H25N3O2S, Mr = 383.5 … Quetiapine
Product Cyclizine has been discontinued in many countries since 2008. Marzine is no longer available. Possible alternatives include the antihistamines dimenhydrinate or meclozine. Structure and properties Cyclizine (C18H22N2, Mr = 266.38 g/mol) is a piperazine derivative. In the drug, it is present as cyclizine hydrochloride. Effects Cyclizine (ATC R06AE03) has antihistamine, antiemetic, antivertiginous, and sedative … Cyclizine
Products Clozapine is commercially available in tablet form (Leponex, generic). It has been approved in many countries since 1972. It is also known as Clozaril in some countries. Clozapine was developed at Wander and Sandoz. Structure and properties Clozapine (C18H19ClN4, Mr = 326.8 g/mol) exists as a yellow crystalline powder that is practically insoluble in … Clozapine
Products Ketoconazole has been approved in many countries since 1981 and is now only commercially available as a shampoo and as a cream for external treatment (Nizoral, generics). Nizoral tablets were taken off the market in 2012 due to declining demand. This article refers to external use. Structure and properties Ketoconazole (C26H28Cl2N4O4, Mr = 531.4 … Ketoconazole
Products Vardenafil is commercially available in the form of film-coated tablets and oral tablets (Levitra, co-marketing drug: Vivanza). It has been approved in many countries since 2003. Generic versions were approved in 2018. Structure and properties Vardenafil (C23H32N6O4S, Mr = 488.6 g/mol) is present in the drugs as vardenafil hydrochloride trihydrate, a piperazine derivative and … Vardenafil
Products In many countries, no drugs containing trimetazidine are commercially available. In other countries, film-coated tablets of modified release and dropper solutions are available (e.g., Vastarel), among others. Structure and properties Trimetazidine (C14H22N2O3, Mr = 266.3 g/mol) is a piperazine derivative. It is present in the drug as trimetazidine dihydrochloride. Effects Trimetazidine (ATC C01EB15) has … Trimetazidine
Products Sildenafil is commercially available in the form of film-coated tablets and as a solution for injection (Viagra, Revatio, generics). It has been approved in many countries since 1998. Generics went on sale July 22, 2013, and the patent expired June 21. Pfizer launched auto-generic sildenafil Pfizer, identical to the original, back in May. In … Sildenafil
Products Trazodone is commercially available in the form of film-coated tablets and sustained-release tablets (Trittico, Trittico retard, Trittico Uno). The active ingredient was developed at Angelini in Italy in 1966 and has been approved in many countries since 1985. Auto-generics and generics are registered. Generic versions of the 100 mg film-coated tablets first went on … Trazodone
Products Epsiprantel is commercially available as a veterinary drug in the form of film-coated tablets. It has been approved in many countries since 1996. Structure and properties Epsiprantel (C20H26N2O2, Mr = 326.4 g/mol) is a piperazine derivative. Effects Epsiprantel (ATC QP52AA04) has antihelminthic activity against common tapeworms found in dogs and cats. Indications Treatment of … Epsiprantel
Products Loxapine has been approved in the EU as a powder for inhalation since 2013 (Adasuve). It was registered in many countries in 2016. Capsules are additionally available in the United States. Structure and properties Loxapine (C18H18ClN3O, Mr = 327.8 g/mol) is present in drugs as loxapine succinate. It is a piperazine derivative and structurally … Loxapine
Products Meclozine is marketed as a fixed combination with caffeine and the vitamin pyridoxine in the form of capsules and suppositories (Itinerol B6). It has been approved in many countries since 1953. In some countries, the active ingredient is also called. Itinerol dragées went out of commerce in 2015. Structure and properties Meclozine (C25H27ClN2, Mr … Meclozin
